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Protein

Peptidoglycan-recognition protein

Gene

PGRP-LB

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseImported
Biological processImmunity, Innate immunityUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidoglycan-recognition proteinUniRule annotation
Gene namesi
Name:PGRP-LBImported
Synonyms:Dmel\CG14704Imported, pgrp-LBImported
ORF Names:CG14704Imported, Dmel_CG14704Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0037906. PGRP-LB.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi50 ↔ 56UniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0037906.
ExpressionAtlasiA4V2P5. differential.

Structurei

3D structure databases

SMRiA4V2P5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 156PGRPInterPro annotationAdd BLAST144
Domaini23 – 162Ami_2InterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IIH1. Eukaryota.
ENOG4111PAY. LUCA.
OrthoDBiEOG091G0O6Z.

Family and domain databases

CDDicd06583. PGRP. 1 hit.
Gene3Di3.40.80.10. 1 hit.
InterProiView protein in InterPro
IPR002502. Amidase_domain.
IPR036505. Amidase_sf.
IPR017331. Peptidoglycan_recognition.
IPR015510. PGRP.
IPR006619. PGRP_domain_met/bac.
PANTHERiPTHR11022. PTHR11022. 1 hit.
PfamiView protein in Pfam
PF01510. Amidase_2. 1 hit.
PIRSFiPIRSF037945. PGRPs. 1 hit.
SMARTiView protein in SMART
SM00644. Ami_2. 1 hit.
SM00701. PGRP. 1 hit.
SUPFAMiSSF55846. SSF55846. 1 hit.

Sequencei

Sequence statusi: Complete.

A4V2P5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQANLGDGV ATARLLSRSD WGARLPKSVE HFQGPAPYVI IHHSYMPAVC
60 70 80 90 100
YSTPDCMKSM RDMQDFHQLE RGWNDIGYSF GIGGDGMIYT GRGFNVIGAH
110 120 130 140 150
APKYNDKSVG IVLIGDWRTE LPPKQMLDAA KNLIAFGVFK GYIDPAYKLL
160 170 180 190 200
GHRQVRDTEC PGGRLFAEIS SWPHFTHIND TEGVSSTTAP VVPHVHPQAA
210
APQKPHQSPP AAPKV
Length:215
Mass (Da):23,602
Last modified:May 29, 2007 - v1
Checksum:iAC661CAEBBE63215
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAN13506.1.
AE014297 Genomic DNA. Translation: AFH06371.1.
AE014297 Genomic DNA. Translation: AFH06372.1.
RefSeqiNP_001247053.1. NM_001260124.2.
NP_001247054.1. NM_001260125.2.
NP_650079.1. NM_141822.3.
NP_731576.1. NM_169393.3.
UniGeneiDm.3374.

Genome annotation databases

EnsemblMetazoaiFBtr0082396; FBpp0081872; FBgn0037906.
FBtr0082397; FBpp0081873; FBgn0037906.
FBtr0082398; FBpp0081874; FBgn0037906.
FBtr0306098; FBpp0297235; FBgn0037906.
FBtr0306099; FBpp0297236; FBgn0037906.
GeneIDi41379.
UCSCiCG14704-RB. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiA4V2P5_DROME
AccessioniPrimary (citable) accession number: A4V2P5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: December 20, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported