A4UUQ0 (A4UUQ0_9VIRU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: PK1A endosialidase EMBL ABP02011.1 EC=3.2.1.129 EMBL ABP02011.1
Organism	Enterobacteria phage K1A EMBL ABP02011.1
Taxonomic identifier	435637 [NCBI]
Taxonomic lineage	Viruses › unclassified phages

Protein attributes

Sequence length	811 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Glycosidase EMBL ABP02011.1 Hydrolase
Gene Ontology (GO)
Molecular function	endo-alpha-(2,8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4UUQ0 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 255936E7388C30A0	FASTA	811	90,352
	10 20 30 40 50 60 MIQRLSSSLV KFKSKIAGAI WRNLDDKLTE VVSLKDFGAK GDGKTNDQDA VNAAMASGKR 70 80 90 100 110 120 IDGAGATYKV SSLPDMERFY NTRFVWERLS GQPLYYVSKG FINGELYKIT DNPYYNAWPQ 130 140 150 160 170 180 DKAFVYENVI YAPYMGSDRH GVSRLHVSWV KSGDDGQTWS TPEWLTDLHP DYPTVNYHCM 190 200 210 220 230 240 SMGVCRNRLF AMIETRTLAK NALTNCALWD RPMSRSLHLT GGITKAANQR YATIHVPDHG 250 260 270 280 290 300 LFVGDFVNFS NSAVTGVSGD MTVATVIDKD NFTVLTPNQQ TSDLNNAGKN WHMGTSFHKS 310 320 330 340 350 360 PWRKTDLGLI PHVTEVHSFA TIDNNGFVMG YHQGDVAPRE VGLFYFPDAF NSPSNYVRRQ 370 380 390 400 410 420 IPSEYEPDAA EPCIKYYDGV LYLITRGTRG DRLGSSLHRS RDIGQTWESL RFPHNVHHTT 430 440 450 460 470 480 LPFAKVGDDL IMFGSERAEN EWEAGAPDDR YKASYPRTFY ARLNVNNWNA ADIEWVNITD 490 500 510 520 530 540 QIYQGDIVNS SVGVGSVVVK DSYIYYIFGG ENHFNPMTYG DNRDKDPFKG HGHPTDIYCY 550 560 570 580 590 600 KMQIANDSRV SRKFTYGATP GQAIPTFMGT DGIRTIPAPL HLSGEVVAAD MTVEHLTLKA 610 620 630 640 650 660 STSANIRSEM LMEREYGFIG KTIPKDNPTA QRVIISGGGG TAADTGAQIT LHGAGSSTSR 670 680 690 700 710 720 RAVYNANEHL FQSGAIMPYN DNVYPAGGPR NRFTTIHLTS DPIITSDATH KYGSQGIDES 730 740 750 760 770 780 VLKAWGKVSF KQYKLIGEMS RGVHHTHFGV LAQDIVAAFA SEGLDAIDFG IVSFEEGQFG 790 800 810 VRYSEILILE AAYTRYRLDK LEEMYATNKI S

References

[1]

"Identification of amino acid residues at the active site of endosialidase that dissociate the polysialic acid binding and cleaving activities in Escherichia coli K1 bacteriophages." Jakobsson E., Jokilammi A., Aalto J., Ollikka P., Lehtonen J.V., Hirvonen H., Finne J. Biochem. J. 405:465-472(2007) [PubMed: 17394421] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A EMBL ABP02011.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EF507428 Genomic DNA. Translation: ABP02011.1.
3D structure databases
ProteinModelPortal	A4UUQ0.
SMR	A4UUQ0. Positions 39-705.
ModBase	Search...
Protein family/group databases
CAZy	GH58. Glycoside Hydrolase Family 58.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023366. ATPase_F1/A1-cplx_a_su_N. IPR024427. Endosialidase_beta_barrel. IPR024428. Endosialidase_beta_prop. IPR024430. Endosialidase_C. IPR024429. Endosialidase_N-extension. IPR001724. Glyco_hydro_58. IPR011040. Neuraminidase. [Graphical view]
Gene3D	G3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit. G3DSA:3.30.750.60. G3DSA:3.30.750.60. 1 hit. G3DSA:4.10.1090.10. G3DSA:4.10.1090.10. 1 hit. G3DSA:2.120.10.10. Neuraminidase. 2 hits.
Pfam	PF12195. End_beta_barrel. 1 hit. PF12217. End_beta_propel. 1 hit. PF12218. End_N_terminal. 1 hit. PF12219. End_tail_spike. 1 hit. [Graphical view]
PRINTS	PR00849. GLHYDRLASE58.
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4UUQ0_9VIRU

Accession

Primary (citable) accession number: A4UUQ0

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)