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Protein
Submitted name:

Aurora kinase A

Gene

Aurka

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • meiotic spindle organization Source: InterPro
  • mitotic centrosome separation Source: InterPro
  • mitotic spindle organization Source: InterPro
  • positive regulation of meiotic cell cycle process involved in oocyte maturation Source: AgBase
  • positive regulation of translation Source: AgBase

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Aurora kinase AImported
Gene namesi
Name:AurkaImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Structurei

3D structure databases

ProteinModelPortaliA4UTN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini132 – 382Protein kinaseInterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0580. Eukaryota.
ENOG410XNRB. LUCA.
HOVERGENiHBG108519.
OrthoDBiEOG091G0EU2.

Family and domain databases

CDDicd14116. STKc_Aurora-A. 1 hit.
InterProiView protein in InterPro
IPR030616. Aur.
IPR030611. AURKA.
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PANTHERiPTHR24350. PTHR24350. 1 hit.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

A4UTN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKCKENCIS GLKTTVPPGD GPKRVPVTQH FPAQHLPSAN SGQAQRVLCP
60 70 80 90 100
SNSSQRLPSH TQKLVSSHKP VQNLKQKQSQ ATSGPRPVSR PLSNTQQSEQ
110 120 130 140 150
PQPAAPGNNP EKEAASKQKN EESKKQWALE DFEIGRPLGK GKFGNVYLAR
160 170 180 190 200
EKQSKFILAL KVLFKTQLEK AGVEHQLRRE VEIQSHLRHP NILRLYGYFH
210 220 230 240 250
DATRVYLILE YAPLGAVYRE LQKLSKFDEQ RTATYITELA NALSYCHSKR
260 270 280 290 300
VIHRDIKPEN LLLGSAGELK IADFGWSVHA PSSRRTTLCG TLDYLPPEMI
310 320 330 340 350
EGRMHDEKVD LWSLGVLCYE FLVGKPPFEA NTYQETYKRI SRVEFTFPDF
360 370 380 390 400
VPEGARDLIS RLLKHNPSHR PTLKEVLEHP WITANSKPAS SHKKESTSKQ

P
Length:401
Mass (Da):45,360
Last modified:May 15, 2007 - v1
Checksum:iA087416646B86D31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF486358 mRNA. Translation: ABO88028.1.
RefSeqiXP_005673093.1. XM_005673036.2.
UniGeneiSsc.1466.

Genome annotation databases

GeneIDi574063.

Similar proteinsi

Entry informationi

Entry nameiA4UTN8_PIG
AccessioniPrimary (citable) accession number: A4UTN8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 31, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)