A4UHF3 (A4UHF3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Indoleamine 2,3-dioxygenase 2 Ensembl ENSMUSP00000113979

Submitted name:
Indoleamine 2,3-dioxygenase-like protein EMBL ABO33433.1
Submitted name:
RIKEN cDNA C230043N17 EMBL EDL32857.1

Gene names

Name:	Ido2 MGI 2142489 Ensembl ENSMUSP00000113979
Synonyms:	C230043N17Rik EMBL EDL32857.1, Indol1 MGI 2142489
ORF Names:	C230043N17 EMBL ABO33433.1, mCG_140344 EMBL EDL32857.1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Dioxygenase EMBL ABO33433.1 Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tryptophan catabolic process to kynurenine Inferred from direct assay Ref.3. Source: MGI
Cellular_component	cytoplasm Inferred from direct assay PubMed 17671174. Source: MGI
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro indoleamine 2,3-dioxygenase activity Inferred from direct assay Ref.3. Source: MGI tryptophan 2,3-dioxygenase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4UHF3 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: DCDFD1A09842E96B	FASTA	405	45,255
	10 20 30 40 50 60 MEPQSQSMTL EVPLSLGRYH ISEEYGFLLP NPLEALPDHY KPWMEIALRL PHLIENRQLR 70 80 90 100 110 120 AHVYRMPLLD CRFLKSYREQ RLAHMALAAI TMGFVWQEGE GQPQKVLPRS LAIPFVEVSR 130 140 150 160 170 180 NLGLPPILVH SDLVLTNWTK RNPEGPLEIS NLETIISFPG GESLRGFILV TVLVEKAAVP 190 200 210 220 230 240 GLKALVQGME AIRQHSQDTL LEALQQLRLS IQDITRALAQ MHDYVDPDIF YSVIRIFLSG 250 260 270 280 290 300 WKDNPAMPVG LVYEGVATEP LKYSGGSAAQ SSVLHAFDEF LGIEHCKESV GFLHRMRDYM 310 320 330 340 350 360 PPSHKAFLED LHVAPSLRDY ILASGPGDCL MAYNQCVEAL GELRSYHINV VARYIISAAT 370 380 390 400 RARSRGLTNP SPHALEDRGT GGTAMLSFLK SVREKTMEAL LCPGA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL32857.1.
[2]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL32857.1.
[3]	"Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice." Ball H.J., Sanchez-Perez A., Weiser S., Austin C.J.D., Astelbauer F., Miu J., McQuillan J.A., Stocker R., Jermiin L.S., Hunt N.H. Gene 396:203-213(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL ABO33433.1.
[4]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000113979.
[5]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000113979.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC114602 Genomic DNA. No translation available. EF137182 mRNA. Translation: ABO33433.1. CH466580 Genomic DNA. Translation: EDL32857.1.
IPI	IPI00153293.
RefSeq	NP_666061.3. NM_145949.2.
UniGene	Mm.219580.
3D structure databases
SMR	A4UHF3. Positions 19-404.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000121992; ENSMUSP00000113979; ENSMUSG00000031549.
GeneID	209176.
KEGG	mmu:209176.
UCSC	uc009ley.2. mouse.
Organism-specific databases
CTD	169355.
MGI	MGI:2142489. Ido2.
Phylogenomic databases
GeneTree	ENSGT00390000002154.
HOGENOM	HOG000190192.
HOVERGEN	HBG006100.
InParanoid	A4UHF3.
KO	K00463.
OMA	GQMHDYV.
Gene expression databases
Genevestigator	A4UHF3.
Family and domain databases
InterPro	IPR000898. Indolamine_dOase. [Graphical view]
Pfam	PF01231. IDO. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	372565.
SOURCE	Search...

Entry information

Entry name

A4UHF3_MOUSE

Accession

Primary (citable) accession number: A4UHF3

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)