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A4TS63

- XYLA_YERPP

UniProt

A4TS63 - XYLA_YERPP

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Protein

Xylose isomerase

Gene

xylA

Organism
Yersinia pestis (strain Pestoides F)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011UniRule annotation
Active sitei104 – 1041UniRule annotation
Metal bindingi232 – 2321Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 2UniRule annotation
Metal bindingi271 – 2711Magnesium 2UniRule annotation
Metal bindingi296 – 2961Magnesium 1UniRule annotation
Metal bindingi307 – 3071Magnesium 2UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi339 – 3391Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Pentose shunt, Xylose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciYPES386656:GKD7-3877-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:YPDSF_3780
OrganismiYersinia pestis (strain Pestoides F)
Taxonomic identifieri386656 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000236: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 439439Xylose isomerasePRO_1000026462Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi386656.YPDSF_3780.

Structurei

3D structure databases

ProteinModelPortaliA4TS63.
SMRiA4TS63. Positions 3-438.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OMAiLFHAHIG.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4TS63-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQSYFNELEQ VRYEGSQSTN PLAFHHYNPD EMILGKRMAD HLRFAACYWH
60 70 80 90 100
TFCWGGADMF GANAFDRPWQ QPGDALALAK RKAEVAFEFF HKLNVPYYCF
110 120 130 140 150
HDVDVSPEGA SLQEYLNNFA VMTDVLAEKQ AASGVKLLWG TANCFTHPRY
160 170 180 190 200
GAGAATNPDP EVFSWAATQV FTAMNATRQL GGENYVLWGG REGYETLLNT
210 220 230 240 250
DLRQEREQIG RFMQMVVEHK HKTGFQGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE KEIKVNIEAN HATLAGHSFH HEIASAIALG IFGSVDANRG
310 320 330 340 350
DPQLGWDTDQ FPNSVEENTL VMFEILKAGG FTTGGLNFDA KVRRQSTDKY
360 370 380 390 400
DLFYGHIGAM DTMALALKFA AKMIEDGQLD QIVAKRYAGW NSELGQQILQ
410 420 430
GKMSLEELSR YASQHNLNPQ HQSGHQELLE NKVNRYLFG
Length:439
Mass (Da):49,550
Last modified:May 15, 2007 - v1
Checksum:iAC04F2193088D5C2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000668 Genomic DNA. Translation: ABP42125.1.
RefSeqiYP_001165098.1. NC_009381.1.

Genome annotation databases

EnsemblBacteriaiABP42125; ABP42125; YPDSF_3780.
GeneIDi5062419.
KEGGiypp:YPDSF_3780.
PATRICi18617677. VBIYerPes122972_4685.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000668 Genomic DNA. Translation: ABP42125.1 .
RefSeqi YP_001165098.1. NC_009381.1.

3D structure databases

ProteinModelPortali A4TS63.
SMRi A4TS63. Positions 3-438.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 386656.YPDSF_3780.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP42125 ; ABP42125 ; YPDSF_3780 .
GeneIDi 5062419.
KEGGi ypp:YPDSF_3780.
PATRICi 18617677. VBIYerPes122972_4685.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000252293.
KOi K01805.
OMAi LFHAHIG.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci YPES386656:GKD7-3877-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pestoides F.

Entry informationi

Entry nameiXYLA_YERPP
AccessioniPrimary (citable) accession number: A4TS63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3