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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Yersinia pestis (strain Pestoides F)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:YPDSF_1077
OrganismiYersinia pestis (strain Pestoides F)
Taxonomic identifieri386656 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181481 – 576Arginine--tRNA ligaseAdd BLAST576

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA4TJL3.
SMRiA4TJL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A4TJL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALLSDK VSQALIAAGA PADCEAQVRQ SAKAQFGDYQ ANGVMAVAKK
60 70 80 90 100
LGMQPRQLAE RVVELLDLTG IASKIEIAGP GFINIFLDRQ WVAEKVEYAL
110 120 130 140 150
TAPKLGVAPV EPQTIVVDYS APNVAKQMHV GHLRSTIIGD AAVRTLAFLG
160 170 180 190 200
HNVIRANHVG DWGTQFGMLI AYLEKMQNEN ASDMGLSDLE LFYQQAKKTY
210 220 230 240 250
DEDEEFALRA RAYVVKLQSG DEYCRQMWRK LVDITMAQNQ VAYDRLNVTL
260 270 280 290 300
TKDDVMGESL YNAMLPEIVA DLKAKGLAVE SEGATVVYLD EYKNKDGEPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLGA DRILYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYVPE SVPLEHHMFG MMLGKDGKPF KTRSGGTVKL SDLLDEAVER
410 420 430 440 450
AGKLIAEKNP DMPADELKQV INAVGIGAVK YADLSKSRTT DYIFDWDNML
460 470 480 490 500
ALDGNTAPYM QYAYTRVVSV FRRAGVDETS LTLPLVVTED REATLATRLL
510 520 530 540 550
QFEEIITTVA REGTPHVMCS YLYDLAGLFS SFYEHCQILN AESEEIRQSR
560 570
LKLAMLTAKT LKQGLDTLGI QTVERM
Length:576
Mass (Da):64,142
Last modified:May 15, 2007 - v1
Checksum:i0C38BDF10B0206E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000668 Genomic DNA. Translation: ABP39475.1.
RefSeqiWP_002211212.1. NZ_CP009715.1.

Genome annotation databases

EnsemblBacteriaiABP39475; ABP39475; YPDSF_1077.
KEGGiypp:YPDSF_1077.
PATRICifig|386656.14.peg.2756.

Similar proteinsi

Entry informationi

Entry nameiSYR_YERPP
AccessioniPrimary (citable) accession number: A4TJL3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: November 22, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families