A4THT4UPPP_YERPPUndecaprenyl-diphosphatase3.6.1.27Bacitracin resistance proteinUndecaprenyl pyrophosphate phosphataseuppPYPDSF_0433Yersinia pestis (strain Pestoides F)BacteriaPseudomonadotaGammaproteobacteriaEnterobacteralesYersiniaceaeYersiniaComplete sequence of chromosome of Yersinia pestis Pestoides F.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphateCell inner membraneMulti-pass membrane proteinBacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.Belongs to the UppP family.Antibiotic resistanceCell inner membraneCell membraneCell shapeCell wall biogenesis/degradationHydrolaseMembranePeptidoglycan synthesisTransmembraneTransmembrane helixMTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM
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