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A4THM0

- UXAB_YERPP

UniProt

A4THM0 - UXAB_YERPP

Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Yersinia pestis (strain Pestoides F)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (15 May 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi18 – 2912NADUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. tagaturonate reductase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciYPES386656:GKD7-375-MONOMER.
    UniPathwayiUPA00246.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
    Alternative name(s):
    Tagaturonate dehydrogenaseUniRule annotation
    Tagaturonate reductaseUniRule annotation
    Gene namesi
    Name:uxaBUniRule annotation
    Ordered Locus Names:YPDSF_0367
    OrganismiYersinia pestis (strain Pestoides F)
    Taxonomic identifieri386656 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000236: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 483483Altronate oxidoreductasePRO_1000044711Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi386656.YPDSF_0367.

    Structurei

    3D structure databases

    ProteinModelPortaliA4THM0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0246.
    HOGENOMiHOG000029586.
    KOiK00041.
    OMAiHNTFCST.
    OrthoDBiEOG6CVVB8.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPiMF_00670. Altron_oxidoreduct.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48179. SSF48179. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4THM0-1 [UniParc]FASTAAdd to Basket

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    MQTLNRRDFP GRSHPDKIIQ FGEGNFLRAF VDWQIDLLNE HTDLNAGIVV    50
    IRPIDTDFPP SLSTQDGLYT AVIRGLNEQG EAVRESRLIR SVNREINIYR 100
    QFDDYLALAR DANIRFMFSN TTEAGIAWNE ADQFSDAPPS SFPAKLTRLL 150
    FERFEHFDGA ADKGWVLLPC ELIDYNGEAL RELVLRYASH WQLPAAFTHW 200
    LTENNTFCST LVDRIVTGYP RDEVAALQTE LGYQDSFLDT AEYFYLFVIQ 250
    GPQGLAQELR LDQLDLNVRI VDDIKPYKER KVAILNGAHT ALVPVAYLSG 300
    LDTVGQTMDD AQISRFVEKT ITEEIVPVLD LPEDELLSFS QAVLSRFRNP 350
    FIQHQLLSIA LNGMTKFRTR ILPQLLTYQQ QKGQLPPRLT FALAALIAFY 400
    RGEREGQTYP LQDDAHWLER YSTLWNGVKH GDIALAELVN RVLSDANHWG 450
    QDLTAVPQLA NQVTEQLQTI LSRGMRAAVA AYS 483
    Length:483
    Mass (Da):54,907
    Last modified:May 15, 2007 - v1
    Checksum:iBDDB13837F6564B4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000668 Genomic DNA. Translation: ABP38782.1.
    RefSeqiYP_001161755.1. NC_009381.1.

    Genome annotation databases

    EnsemblBacteriaiABP38782; ABP38782; YPDSF_0367.
    GeneIDi5064924.
    KEGGiypp:YPDSF_0367.
    PATRICi18609524. VBIYerPes122972_0687.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000668 Genomic DNA. Translation: ABP38782.1 .
    RefSeqi YP_001161755.1. NC_009381.1.

    3D structure databases

    ProteinModelPortali A4THM0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 386656.YPDSF_0367.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP38782 ; ABP38782 ; YPDSF_0367 .
    GeneIDi 5064924.
    KEGGi ypp:YPDSF_0367.
    PATRICi 18609524. VBIYerPes122972_0687.

    Phylogenomic databases

    eggNOGi COG0246.
    HOGENOMi HOG000029586.
    KOi K00041.
    OMAi HNTFCST.
    OrthoDBi EOG6CVVB8.

    Enzyme and pathway databases

    UniPathwayi UPA00246 .
    BioCyci YPES386656:GKD7-375-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPi MF_00670. Altron_oxidoreduct.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48179. SSF48179. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Pestoides F.

    Entry informationi

    Entry nameiUXAB_YERPP
    AccessioniPrimary (citable) accession number: A4THM0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: May 15, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3