A4THK0 (MTGA_YERPP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Monofunctional biosynthetic peptidoglycan transglycosylase
Short name=Monofunctional TGase
EC=2.4.2.-

Gene names

Name:	mtgA
Ordered Locus Names:	YPDSF_0345

Organism

Yersinia pestis (strain Pestoides F) [Complete proteome] [HAMAP]

Taxonomic identifier

386656 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia › Yersinia pestis

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation By similarity.
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00766
Subcellular location	Cell membrane; Single-pass membrane protein Potential HAMAP-Rule MF_00766.
Sequence similarities	Belongs to the glycosyltransferase 51 family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan-based cell wall Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transferase activity, transferring pentosyl groups Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Monofunctional biosynthetic peptidoglycan transglycosylase HAMAP-Rule MF_00766		PRO_1000017319
Regions
	Transmembrane	18 – 38	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	A4THK0 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 76F186AEFA04B1D1	FASTA	241	27,096
	10 20 30 40 50 60 MISVRRGFSQ LWYWGKRGVI GIIALWMAGI LIFAFLPVPF SMVMIERQLG AWLTGDFAYV 70 80 90 100 110 120 AHSDWVPMDE ISPYMALAVM AAEDQKFPDH WGFDVGAIES ALSHNQRNQK RIRGASTLSQ 130 140 150 160 170 180 QTAKNVFLWD GRSWVRKGLE VGLTAGIELI WTKRRILTVY LNIAEFGNGI FGVEAAARHF 190 200 210 220 230 240 FNKPASKLSA SEAALLAAVL PNPLRFKVNA PSGYVISRQQ WILRQMHQLG GKTFLQENTL D

References

[1]

"Complete sequence of chromosome of Yersinia pestis Pestoides F." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Di Bartolo G., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F. , Land M., Hauser L., Worsham P., Chu M., Bearden S., Garcia E., Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Pestoides F.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000668 Genomic DNA. Translation: ABP38762.1.
RefSeq	YP_001161735.1. NC_009381.1.
3D structure databases
ProteinModelPortal	A4THK0.
ModBase	Search...
Protein-protein interaction databases
STRING	386656.YPDSF_0345.
Protein family/group databases
CAZy	GT51. Glycosyltransferase Family 51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABP38762; ABP38762; YPDSF_0345.
GeneID	5064901.
KEGG	ypp:YPDSF_0345.
PATRIC	18609474. VBIYerPes122972_0662.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0744.
HOGENOM	HOG000288117.
KO	K03814.
OMA	LTYMIEH.
ProtClustDB	PRK00056.
Enzyme and pathway databases
UniPathway	UPA00219.
Family and domain databases
HAMAP	MF_00766. Mono_pep_trsgly.
InterPro	IPR001264. Glyco_trans_51. IPR011812. Mono_pep_trsgly. [Graphical view]
Pfam	PF00912. Transgly. 1 hit. [Graphical view]
TIGRFAMs	TIGR02070. mono_pep_trsgly. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MTGA_YERPP

Accession

Primary (citable) accession number: A4THK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 15, 2007
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program