A4TF55 (A4TF55_MYCGI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338
Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338

Gene names

Ordered Locus Names:

Mflv_4746

Organism

Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]

Taxonomic identifier

350054 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	167 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338
Catalytic activity	5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338
Sequence similarities	Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Ontologies

Keywords
Biological process	Purine biosynthesis PIRNR PIRNR001338
Molecular function	Isomerase PIRNR PIRNR001338 Lyase EMBL ABP47214.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-(carboxyamino)imidazole ribonucleotide mutase activity Inferred from electronic annotation. Source: EC phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4TF55 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 5641DE0AEB35D36D	FASTA	167	17,253
	10 20 30 40 50 60 MSSPRVGLIM GSDSDWPVMS DAAEALAEFE VPFEVGVVSA HRTPARMLTY AQEASGRGIE 70 80 90 100 110 120 VIIAGAGGAA HLPGMVASAT PLPVIGVPVP LARLDGMDSL LSIVQMPAGV PVATVSIGGA 130 140 150 160 RNAGLLAVRI LGASDNALQQ RMIAFQASLE QMVLQKEEAL RQKLLGE

References

[1]

"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PYR-GCK.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000656 Genomic DNA. Translation: ABP47214.1.
RefSeq	YP_001136002.1. NC_009338.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4TF55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000022796; EBMYCP00000022458; EBMYCG00000022791.
GeneID	4976058.
GenomeReviews	Gene locus Mflv_4746 in contig CP000656_GR.
KEGG	mgi:Mflv_4746.
PATRIC	18037756. VBIMycGil17082_4844.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0041.
GeneTree	EBGT00050000016911.
HOGENOM	HBG301965.
OMA	LIMGSDS.
PhylomeDB	A4TF55.
ProtClustDB	CLSK2321239.
Family and domain databases
InterPro	IPR024694. N5-CAIR_mutase_PurE. IPR000031. N5-CAIR_Mutase_PurE_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.7700. AIR_carboxyl. 1 hit.
KO	K01588.
Pfam	PF00731. AIRC. 1 hit. [Graphical view]
PIRSF	PIRSF001338. AIR_carboxylase. 1 hit.
SMART	SM01001. AIRC. 1 hit. [Graphical view]
SUPFAM	SSF52255. AIR_carboxyl. 1 hit.
TIGRFAMs	TIGR01162. PurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4TF55_MYCGI

Accession

Primary (citable) accession number: A4TF55

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)