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Protein

Glutamate decarboxylase

Gene

Mflv_4935

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Mflv_4935Imported
OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))Imported
Taxonomic identifieri350054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000232 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei279N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi350054.Mflv_4935

Structurei

3D structure databases

ProteinModelPortaliA4TEM4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

A4TEM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNVSRHSSL APAYTGRMSM SPVPALRLPD ESMEPEQAYR FIHDELMLDG
60 70 80 90 100
SSRLNLATFV TTWMDPEAGQ LMSETFDKNM IDKDEYPVTA AIEQRCVCMV
110 120 130 140 150
ADLFHAENLR DDDPSTAIGV STVGSSEAVM LAGLAMKWRW RDKFAGKDGD
160 170 180 190 200
GWKGRTPNLV MGSNVQVVWE KFCRYFDVEA RYLPMEKGRY VITPEQVLDA
210 220 230 240 250
VDEDTIGVVA ILGTTFTGEL EPVAEICAAL DALAAGGGCD VPVHVDAASG
260 270 280 290 300
GFVVPFLNPL LVWDFRLPRV VSINVSGHKY GLTYPGIGFV VWRNAEHLPE
310 320 330 340 350
DLVFRVNYLG GDMPTFTLNF SRPGNQVVGQ YYNFLRLGRD GYTQVMHALA
360 370 380 390 400
DTAQWLAREL EGMTGSDHKP VFEVITDGSA IPVVAFRLTE GAKFTVFDIS
410 420 430 440 450
ALLRSYGWQV PAYTMPEDAT DIAVLRIVVR EGFSANLARA LRDDLREVLG
460
KLDKVGIGGF SDEEHFAH
Length:468
Mass (Da):51,707
Last modified:May 15, 2007 - v1
Checksum:iF8B73400E0062D48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000656 Genomic DNA Translation: ABP47401.1
RefSeqiWP_011895765.1, NC_009338.1

Genome annotation databases

EnsemblBacteriaiABP47401; ABP47401; Mflv_4935
KEGGimgi:Mflv_4935

Similar proteinsi

Entry informationi

Entry nameiA4TEM4_MYCGI
AccessioniPrimary (citable) accession number: A4TEM4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: April 25, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health