A4TEJ4 (RS4_MYCGI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	Mflv_4971

Organism

Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]

Taxonomic identifier

350054 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP MF_01306_B With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP MF_01306_B
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	30S ribosomal protein S4 HAMAP MF_01306_B		PRO_1000085980
Regions
	Domain	91 – 151	61	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	A4TEJ4 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: E33C7670C49CCB78	FASTA	201	23,292
	10 20 30 40 50 60 MARYTGPVTR KSRRLGVDLV GGDQSFEKRP YPPGQHGRAR IKESEYRTQL QEKQKARFTY 70 80 90 100 110 120 GVMEKQFRRY YEEANRLPGK TGDNLLRILE SRLDNVVYRA GLARTRRMAR QLVSHGHFTV 130 140 150 160 170 180 NGVKVDVPSY RVSQYDIIDV KDKSINTLPF EVARQTAGER PIPGWLQVVG ERQRILVHQL 190 200 PERAQIDVPL TEQLIVELYS K

References

[1]

"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PYR-GCK.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000656 Genomic DNA. Translation: ABP47437.1.
RefSeq	YP_001136225.1. NC_009338.1.
3D structure databases
ProteinModelPortal	A4TEJ4.
SMR	A4TEJ4. Positions 41-201.
ModBase	Search...
Protein-protein interaction databases
STRING	A4TEJ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000025976; EBMYCP00000025638; EBMYCG00000025971.
GeneID	4976282.
GenomeReviews	Gene locus Mflv_4971 in contig CP000656_GR.
KEGG	mgi:Mflv_4971.
PATRIC	18038204. VBIMycGil17082_5068.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0522.
GeneTree	EBGT00050000017415.
HOGENOM	HBG285740.
OMA	QLVVELY.
PhylomeDB	A4TEJ4.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	MGIL350054:MFLV_4971-MONOMER.
Family and domain databases
HAMAP	MF_01306_B. Ribosomal_S4_B. [Tree]
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.1050.10. G3DSA:1.10.1050.10. 1 hit. G3DSA:3.10.290.10. G3DSA:3.10.290.10. 1 hit.
KO	K02986.
PANTHER	PTHR11831. Ribosomal_S4. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. RpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_MYCGI

Accession

Primary (citable) accession number: A4TEJ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 15, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program