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Protein
Submitted name:

PAS/PAC sensor hybrid histidine kinase

Gene

Mflv_4423

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
PAS/PAC sensor hybrid histidine kinaseImported (EC:2.7.13.3Imported)
Gene namesi
Ordered Locus Names:Mflv_4423Imported
OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))Imported
Taxonomic identifieri350054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000000232 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei6544-aspartylphosphatePROSITE-ProRule annotation1

Keywords - PTMi

PhosphoproteinPROSITE-ProRule annotation

Interactioni

Protein-protein interaction databases

STRINGi350054.Mflv_4423

Structurei

3D structure databases

ProteinModelPortaliA4TDH5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini328 – 544Histidine kinaseInterPro annotationAdd BLAST217
Domaini605 – 721Response regulatoryInterPro annotationAdd BLAST117
Domaini737 – 767PASInterPro annotationAdd BLAST31

Phylogenomic databases

eggNOGiENOG4105BZU Bacteria
ENOG410XNMH LUCA
HOGENOMiHOG000217841
OMAiRSYQAQQ
OrthoDBiPOG091H03T5

Family and domain databases

CDDicd00075 HATPase_c, 2 hits
cd00082 HisKA, 1 hit
cd00130 PAS, 1 hit
cd00156 REC, 1 hit
Gene3Di3.30.450.40, 1 hit
3.30.565.10, 2 hits
3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR011006 CheY-like_superfamily
IPR029016 GAF-like_dom_sf
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR005467 His_kinase_dom
IPR003661 HisK_dim/P
IPR036097 HisK_dim/P_sf
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013656 PAS_4
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
IPR004358 Sig_transdc_His_kin-like_C
IPR001789 Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF02518 HATPase_c, 1 hit
PF13581 HATPase_c_2, 1 hit
PF00512 HisKA, 1 hit
PF08448 PAS_4, 1 hit
PF13426 PAS_9, 1 hit
PF00072 Response_reg, 1 hit
PF07228 SpoIIE, 1 hit
PRINTSiPR00344 BCTRLSENSOR
SMARTiView protein in SMART
SM00387 HATPase_c, 2 hits
SM00388 HisKA, 1 hit
SM00331 PP2C_SIG, 1 hit
SM00448 REC, 1 hit
SUPFAMiSSF47384 SSF47384, 1 hit
SSF52172 SSF52172, 1 hit
SSF55785 SSF55785, 2 hits
SSF55874 SSF55874, 2 hits
TIGRFAMsiTIGR00229 sensory_box, 1 hit
PROSITEiView protein in PROSITE
PS50109 HIS_KIN, 1 hit
PS50112 PAS, 1 hit
PS50110 RESPONSE_REGULATORY, 1 hit

Sequencei

Sequence statusi: Complete.

A4TDH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNWAQTPLGP TSEWPQSLQT AANILLSSRF PMWMAWGPDL TFFCNDAYRN
60 70 80 90 100
VTLGRKYPWA LGRPASEVWA EIWDDIGPRI ERVLSTGVAT WDTSLLLFLE
110 120 130 140 150
RSGYTEESYH TFSYSPLRDD DGAVVGMLCV VSEDTLQVIG ERRMATLRDL
160 170 180 190 200
GSDPSVVRTE GEILSFVDRQ LAQNLRDLPF TLTYLFDDDG SAHLAGMSGI
210 220 230 240 250
TGDHPAAPDV LTGADGELWP VGPPAGGETV LLEVDTAPYP AMPTGDWREP
260 270 280 290 300
PRQVLIVPLL QQGAAPTGFL VAGLNRYRVL DDAYRGFVAL VAGHIAAGIG
310 320 330 340 350
LSRSYRTQQM RAEELAELDR AKTTFFSNIS HEFRTPLTLI LDPVSELRRA
360 370 380 390 400
DTLGDAARQE LDVVWRNGLR LNKLVNTLLD FSRIEAGRTQ AHYQPVDLGA
410 420 430 440 450
VTAELASVFR SAIERAGLVF DVDCPPLGEE AYVDLDMWEK VIFNLLSNAL
460 470 480 490 500
KFTFEGSVSV TARRDGRGAV ITVSDTGTGV PADEMPRLFE RFHRIENTRA
510 520 530 540 550
RSNEGSGIGL ALVKELVGLH GGTIEADSAE SRGTTFTIRL PWGAGHLPAD
560 570 580 590 600
AVASQPRERR PGNTVDAYVE EALRWTPDGV REYVAESAQP TTGPEKPIGT
610 620 630 640 650
GTLARVLVAD DNADMREYLG RLLRSDGYAV EAVVDGWQAL EAIRAEPPDL
660 670 680 690 700
VISDVMMPRL DGLGLVAELR ADRRTAAVPV LLLSARAGQE ASISGLQAGA
710 720 730 740 750
DDYLVKPFAA AELLARVRAN IQLARLREGH ARWRTALVDS LQEAFFVCDE
760 770 780 790 800
HGAVVEINPA FTEILGYDST GLPYPLMHPW WPLKGSDAEA NRRVEEAFGS
810 820 830 840 850
FMRDPHGTLT EVPVTHRDGH RLYVTVTFSH ADDPETGRDV IVGTLRDVTA
860 870 880 890 900
ERYIVQRESA LASLNEKLAQ ADTLDDAVLA AAEEFSSIWS ARRVVAATWP
910 920 930 940 950
DEPDGEHESD APSLTVVGAP ATWDGLPGSA RELILTLRRD HLLAPHTSDA
960 970 980 990 1000
GAAGVALRHP RGVLVLYVEL PEQRLFTAED DTLLTVLAGR LGQGLQRVHQ
1010 1020 1030 1040 1050
IDQQRETALA LQHAILGPSL SSAFAVRYQP ATRPLQVGGD WYDVVDLEDG
1060 1070 1080 1090 1100
RIGLIVGDCV GHGLAAATVM GQLRSACRAL LLEHPSPAAA LSALDRFAAR
1110 1120 1130 1140 1150
LPGARCTTAF CAVLDPRIGE VVYSCAGHPP PIMVTADRTT ELLEGARATP
1160 1170 1180 1190 1200
LGLKNPPHRT EARVTMPARA TLLLYTDGLV ERRRESIDDG IARATDVVQG
1210 1220 1230 1240 1250
NRATDLDQLA NVIMARLAPA DGYHDDVALL LYRQPEPLDL DFPADVAELA
1260 1270 1280 1290 1300
GSRTVLRGWL DSAGVPQDQA LDVLIAVGEA LANAIEHGHR DDPGGRVRLR
1310 1320 1330 1340 1350
AVALPDRVQL TIIDTGSWKA PDDVPALHRG RGIALMKALM QDVTIDSQTT
1360
GTTVHMNTRI A
Length:1,361
Mass (Da):147,938
Last modified:May 15, 2007 - v1
Checksum:i62B0CF646B077716
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000656 Genomic DNA Translation: ABP46892.1

Genome annotation databases

EnsemblBacteriaiABP46892; ABP46892; Mflv_4423
KEGGimgi:Mflv_4423

Similar proteinsi

Entry informationi

Entry nameiA4TDH5_MYCGI
AccessioniPrimary (citable) accession number: A4TDH5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: May 23, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health