Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4TCE3 (MQO_MYCGI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:Mflv_4052
OrganismMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]
Taxonomic identifier350054 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length518 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 518518Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000078033

Sequences

Sequence LengthMass (Da)Tools
A4TCE3 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: BD59AFE2E14F142E

FASTA51855,788
        10         20         30         40         50         60 
MSEAEKTDVL LVGAGIMSAT LCALLRLLEP NWSMTLVERL DGAAAESSDP WNNAGTGHSA 

        70         80         90        100        110        120 
LCELNYTPAR PDGSIDIAKA VNVNEQFQVS RQFWTYAVEN GVLPDVRSFL NPIPHVSFVT 

       130        140        150        160        170        180 
GADNVQYLRK RYEALVGNPL FGTMEFIDDA GEFARRLPLM AEGRDLREPV GLNWTQDGTD 

       190        200        210        220        230        240 
VDFGALSRQL LGFGAQQGMD TLFGHDVTNL SQNSDSTWTV KVVNRRTGRK RTFNAKFVFV 

       250        260        270        280        290        300 
GAGGGALPLL QKAGIKEAKG FGGFPVGGQW LRTGNPELTA KHQAKVYGLP PLGAPPMSVP 

       310        320        330        340        350        360 
HLDTRVINDK SWLLFGPFAG WSPKFLKQGK VTDLPFSVKP DNLVSMLGVG LTEMGLLKYL 

       370        380        390        400        410        420 
IGQLLLSEAA RVENLREFAP SAKDSDWELD IAGQRVQVIR KAKGKGGVLE FGTTVLSAAD 

       430        440        450        460        470        480 
GSIAGLLGAS PGASTAVPAM FDVMKRCFAD RYPSWEPKLK EMVPSLGVTL SDEPKLFEEV 

       490        500        510 
WARGTKVLKL DKPAGAIPAT TDGQSTAGTE HTPTAATV

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PYR-GCK.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000656 Genomic DNA. Translation: ABP46522.1.
RefSeqYP_001135310.1. NC_009338.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4TCE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000025784; EBMYCP00000025446; EBMYCG00000025779.
GeneID4975366.
GenomeReviewsGene locus Mflv_4052 in contig CP000656_GR.
KEGGmgi:Mflv_4052.
PATRIC18036311. VBIMycGil17082_4126.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
GeneTreeEBGT00050000015585.
HOGENOMHBG289663.
OMAKKWVPLM.
PhylomeDBA4TCE3.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycMGIL350054:MFLV_4052-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_MYCGI
AccessionPrimary (citable) accession number: A4TCE3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents