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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei164UniRule annotation1
Active sitei596UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Mflv_3706Imported
OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))Imported
Taxonomic identifieri350054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000232 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi350054.Mflv_3706.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
HOGENOMiHOG000238647.
KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PANTHERiPTHR30523. PTHR30523. 1 hit.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A4TC23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSSPATPDQ SLEPIGAVQR TQVGREATEP MREDIRLLGT ILGDTVREQN
60 70 80 90 100
GDEVFDLVER ARVEAFRVRR SEIDRADMAK LFDDVDVHRA IPVIRAFTHF
110 120 130 140 150
ALLANVAEDI HRERRRRIHE AAGEPPQDSR LDATYLKLDD AGLDAGAVAD
160 170 180 190 200
ALAGALVSPV ITAHPTETRR RTVFDTQHRI TELMRLRLHG HDTSPDGRDV
210 220 230 240 250
EQELRRHILT LWQTALIRLS RLKIQDEIET GLRYYEAALF EVIPQVNAEV
260 270 280 290 300
RAALQQRFPE AGLLEQPIVR PGSWIGGDRD GNPNVTAEVV RLATGSAAYT
310 320 330 340 350
ALAHYFAELT GLEQELSMSA RLVHITDELA ALADSCHEPA RADEPYRRAL
360 370 380 390 400
RVVHARLTAT AQQILDRQPE HELDLGMEPY AAPGELLDDL DVIDASLRAN
410 420 430 440 450
GSAVLADDRL GRLREAVRVF GFHLSGLDMR QNSDVHEEVV AELLAWAGVH
460 470 480 490 500
SDYTSLSEDD RVEVLAAELA TRRPLTSPDA DLSELARKEL DIVAAAARAV
510 520 530 540 550
HVFGPQAVPN YIISMCQSVS DMLEAAILLK EAGLLDASSE HPYAPVGIVP
560 570 580 590 600
LFETIDDLQR GSSILEAALE LPLYRGLVSA RGDSQEVMLG YSDSNKDGGY
610 620 630 640 650
LAANWALYRA ELELVESSRK TGIRLRLFHG RGGTVGRGGG PSYDAILAQP
660 670 680 690 700
PGAVQGSLRI TEQGEVIAAK YAEPRIAHRN LETLLAATLE ATLLDMEGLG
710 720 730 740 750
DLAGTAYEVL DDLAARAQRA YAELVHDTPG FVDYFKASTP VSEIGALNIG
760 770 780 790 800
SRPTSRKPTT SISDLRAIPW VLAWSQSRVM LPGWYGTGTA FEDYVGDGDD
810 820 830 840 850
AEARLQVLQD LYRRWPFFAT VLSNMAQVLA KSDLGLAAHY SELVEDEELR
860 870 880 890 900
RRVFDKIVDE HARTIRMHRL ITGHEDLLAD NPSLARSVFN RFPYLEPLNH
910 920 930
LQVELLRRYR SGDEDDLVQR GILLTMSGLA TALRNSG
Length:937
Mass (Da):103,429
Last modified:May 15, 2007 - v1
Checksum:i1AC153C494C8F9B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000656 Genomic DNA. Translation: ABP46178.1.
RefSeqiWP_011894558.1. NC_009338.1.

Genome annotation databases

EnsemblBacteriaiABP46178; ABP46178; Mflv_3706.
KEGGimgi:Mflv_3706.

Similar proteinsi

Entry informationi

Entry nameiA4TC23_MYCGI
AccessioniPrimary (citable) accession number: A4TC23
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported