A4T9Y3 (A4T9Y3_MYCGI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK HAMAP MF_00361
Ordered Locus Names:	Mflv_3508

Organism

Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]

Taxonomic identifier

350054 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361 SAAS SAAS002504
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361 SAAS SAAS002504
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361 SAAS SAAS002504
Subcellular location	Cytoplasm By similarity HAMAP MF_00361 SAAS SAAS002504.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361 SAAS SAAS002504
Ligand	ATP-binding HAMAP MF_00361 SAAS SAAS002504 NAD HAMAP MF_00361 SAAS SAAS002504 NADP HAMAP MF_00361 SAAS SAAS002504 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 SAAS SAAS002504 EMBL ABP45982.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4T9Y3 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: F55141FCB42407C9	FASTA	314	33,673
	10 20 30 40 50 60 MTAPVTDNSP ERTILLVVHT GRPEATEVAR RVEKVLADHG IGLRVLSAEA VDRGPLHLSP 70 80 90 100 110 120 DDMRALGADI EVVDPEERAA EGCELVLVLG GDGTFLRAAE LARNAEIPVL GVNLGKIGFL 130 140 150 160 170 180 AEAEAEAIDT VLDHIVRRDY RVEERMTLDV AVRAKGEIID HGWALNEASL EKGPRLGVLG 190 200 210 220 230 240 VVVEVDGRPV SSFGCDGVLV STPTGSTAYA FSAGGPVLWP DLEAIIVVPN NAHALFARPM 250 260 270 280 290 300 VTSPDAAIAI EIEASGYDAL VFCDGRREMV LPAGGRLEVT RCATPLKWVR LDSAPFTDRL 310 VRKFRLPVTG WRGQ

References

[1]

"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PYR-GCK.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000656 Genomic DNA. Translation: ABP45982.1.
RefSeq	YP_001134770.1. NC_009338.1.
3D structure databases
ProteinModelPortal	A4T9Y3.
SMR	A4T9Y3. Positions 9-312.
ModBase	Search...
Protein-protein interaction databases
STRING	A4T9Y3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000026641; EBMYCP00000026303; EBMYCG00000026636.
GeneID	4974826.
GenomeReviews	Gene locus Mflv_3508 in contig CP000656_GR.
KEGG	mgi:Mflv_3508.
PATRIC	18035174. VBIMycGil17082_3567.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0061.
GeneTree	EBGT00050000016530.
HOGENOM	HBG713904.
OMA	GPVVWPE.
ProtClustDB	PRK03372.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4T9Y3_MYCGI

Accession

Primary (citable) accession number: A4T9Y3

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)