A4T9K1 (A4T9K1_MYCGI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, alpha subunit EMBL ABP46110.1
EC=2.7.7.7 EMBL ABP46110.1

Gene names

Ordered Locus Names:

Mflv_3636

Organism

Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]

Taxonomic identifier

350054 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	1183 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4T9K1 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: A9259BF0C311A6EB	FASTA	1,183	129,000
	10 20 30 40 50 60 MSGSFVHLHN HTEYSMLDGA AKVKPMLAEA QRLEMPAIGM TDHGNMFGAS EFYNAATDAG 70 80 90 100 110 120 IKPIIGIEAY IAPASRFDTK RVLWGDPGQK SDDVSGSGSY THMTMVAENA TGLRNLFKLS 130 140 150 160 170 180 SLASFEGQLG KWSRMDAEII AEHAEGIIAT TGCPSGEVQT RLRLGHDREA LEAAARWREI 190 200 210 220 230 240 FGPENFFLEL MDHGLDIERR VREGLLEIGQ KLGIPPLATN DCHYVTRDAS QNHEALLCIQ 250 260 270 280 290 300 TGKTLSDPNR FKFDGDGYYL KSAAEMRALW DGQVPGACDS TLLIAERVQP YTDVWAPKDR 310 320 330 340 350 360 MPVFPVPEGH DQGSWLTHEV MAGLERRFSA AAGGQVPPEY IERADYEIKV ICDKGFPAYF 370 380 390 400 410 420 LIVADLINYA KSVGIRVGPG RGSAAGSLVA YAMGITNIDP IPHGLLFERF LNPERPSAPD 430 440 450 460 470 480 IDIDFDDRRR GEMLRYAANK WGSDRVAQVI TFGTIKTKAA LKDSARVHYG QPGFAIADRI 490 500 510 520 530 540 TKALPPPIMA KDIPVSGITD PTHERYKEAA EVRALIDTDP DVRTIYETAR GLEGLVRNAG 550 560 570 580 590 600 VHACAVIMSS EPLIDAIPLW KRPQDGAVIT GWDYPSCEAI GLLKMDFLGL RNLTIIGDCI 610 620 630 640 650 660 ENIKANRGVD VDLESLALDD PKAYELLGRG DTLGVFQLDG SAMRDLLRRM QPTEFNDIVA 670 680 690 700 710 720 VLALYRPGPM GMNAHNDYAD RKNGRQPIKP IHPELEEPLK DILAETYGLI VYQEQIMFIA 730 740 750 760 770 780 QKVASYSMGK ADALRKAMGK KKLEVLEAEY KGFKEGMTAN GFSEGAVKAL WDTILPFAGY 790 800 810 820 830 840 AFNKSHAAGY GLVSYWTAYL KANYQAEYMA GLLTSVGDDK DKAAIYLADC RRLGITVLPP 850 860 870 880 890 900 DVNESVQNFA SVGDDIRFGL GAVRNVGANV VASLVSTREE KGKYTDFSDY LNKIDITACT 910 920 930 940 950 960 KKVTESLIKA GAFDSLGHPR KGLFLVHTDA VDSVLGTKKA EAMGQFDLFG GGDDDGDTGD 970 980 990 1000 1010 1020 SAFTIKVPDE EWEDKHKLAL EREMLGLYVS GHPLNGIAHL LTAQVDTQIP AILEGAIPND 1030 1040 1050 1060 1070 1080 AQVRVGGILA SVNRRVNKNG LPWASAQIED LSGGIEVLFF PQTYSMFGAE IADDVVVLVG 1090 1100 1110 1120 1130 1140 AKVAKRDDRI SLIANELIVP DFTSAQVNRP VAVSLPTRQC TVDKVTALKQ VLARHPGTAQ 1150 1160 1170 1180 VHLRLISGER ITTLELDQSL RVTPSSALMG DLKELLGPGC LGG

References

[1]

"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PYR-GCK.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000656 Genomic DNA. Translation: ABP46110.1.
RefSeq	YP_001134898.1. NC_009338.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4T9K1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000022787; EBMYCP00000022449; EBMYCG00000022782.
GeneID	4974954.
GenomeReviews	Gene locus Mflv_3636 in contig CP000656_GR.
KEGG	mgi:Mflv_3636.
PATRIC	18035442. VBIMycGil17082_3696.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
GeneTree	EBGT00050000016568.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4T9K1_MYCGI

Accession

Primary (citable) accession number: A4T9K1

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)