A4T9I2 (A4T9I2_MYCGI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Ordered Locus Names:

Mflv_3657

Organism

Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]

Taxonomic identifier

350054 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL ABP46131.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	157	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	A4T9I2 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: B0D2843F05CADF16	FASTA	268	28,430
	10 20 30 40 50 60 MTLLQGKRIL VTGIITDSSI AFHIAKVAQE AGAELVLTGF DRMKLIQRIA DRLPEKAPLL 70 80 90 100 110 120 ELDVQNSEHL DSLADRVSEV IGEGNKLDGV VHSIGFMPQT GMGINPFFDA PYEDVAKGIH 130 140 150 160 170 180 ISAYSYASLA KAVLPIMNPG GGIVGMDFDP TRAMPAYNWM TVAKSALESV NRFVAREAGK 190 200 210 220 230 240 VGVRSNLVAA GPIRTLAMSA IVGGALGDEA GAQMQLLEEG WDQRAPLGWN MKDPTPVAKT 250 260 VCALLSDWLP ATTGTVIFAD GGASTQLL

References

[1]

"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PYR-GCK.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000656 Genomic DNA. Translation: ABP46131.1.
RefSeq	YP_001134919.1. NC_009338.1.
3D structure databases
ProteinModelPortal	A4T9I2.
SMR	A4T9I2. Positions 3-268.
ModBase	Search...
Protein-protein interaction databases
STRING	A4T9I2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000027243; EBMYCP00000026905; EBMYCG00000027238.
GeneID	4974975.
GenomeReviews	Gene locus Mflv_3657 in contig CP000656_GR.
KEGG	mgi:Mflv_3657.
PATRIC	18035484. VBIMycGil17082_3717.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
GeneTree	EBGT00050000015205.
HOGENOM	HBG750976.
OMA	DCDVGSD.
ProtClustDB	PRK07889.
Family and domain databases
InterPro	IPR014358. Enoyl-ACP_Rdtase_NADH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K11611.
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4T9I2_MYCGI

Accession

Primary (citable) accession number: A4T9I2

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)