Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A4T8M4

- SYR_MYCGI

UniProt

A4T8M4 - SYR_MYCGI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMGIL350054:GHK8-2318-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mflv_2296
OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Taxonomic identifieri350054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000232: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Arginine--tRNA ligasePRO_1000076222Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi350054.Mflv_2296.

Structurei

3D structure databases

ProteinModelPortaliA4T8M4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi130 – 14011"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiIRNTIND.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4T8M4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPADLAQLL KATAAAVLAE HGLDSAALPD TVTVERPRNP EHGDYATNLA
60 70 80 90 100
LQLGKKVGAN PRELAGWLAE ALAASDGIAA ADVAGPGFVN LRIEASAQNV
110 120 130 140 150
MVSNVLSAGA DYGHSAVLAG KKVNLEFVSA NPTGPIHIGG TRWAAVGDAL
160 170 180 190 200
GRLLTTQGAA VTREYYFNDH GAQIDRFSNS LIAAAKGEPA PEDGYAGTYI
210 220 230 240 250
ADIASQVVAK EPGVLDQPDD RMRETFRAIG VNLMFDHIKE SLHEFGTDFD
260 270 280 290 300
VYTHEDSMHT SGRVEQAIDK LRETGFAYEK DGAVWLRTTD FGDDKDRVVI
310 320 330 340 350
KSDGKPAYIA GDLAYFLDKR KRGFDLCIYM LGADHHGYIA RLKASAAALG
360 370 380 390 400
DDPDTVEVLI GQMVNLVRDG QPVRMSKRAG TVITLDDLVE AIGVDAARYS
410 420 430 440 450
LIRSSVDTPI DIDLELWSSA SNENPVYYVQ YAHARLSALA RNAAELGIAP
460 470 480 490 500
DTAHLDLLTH DKEGVLIRNI GEFPRILATA AELREPHRVS RYLEDLAGDY
510 520 530 540 550
HRFYDACRVL PQGDEAPGDL HAARLALCAA TRQVIANGLD ILGVSAPERM
Length:550
Mass (Da):59,204
Last modified:May 15, 2007 - v1
Checksum:iA47BAA39AC88EA57
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000656 Genomic DNA. Translation: ABP44774.1.
RefSeqiWP_011893179.1. NC_009338.1.
YP_001133562.1. NC_009338.1.

Genome annotation databases

EnsemblBacteriaiABP44774; ABP44774; Mflv_2296.
GeneIDi4973619.
KEGGimgi:Mflv_2296.
PATRICi18032709. VBIMycGil17082_2348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000656 Genomic DNA. Translation: ABP44774.1 .
RefSeqi WP_011893179.1. NC_009338.1.
YP_001133562.1. NC_009338.1.

3D structure databases

ProteinModelPortali A4T8M4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 350054.Mflv_2296.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP44774 ; ABP44774 ; Mflv_2296 .
GeneIDi 4973619.
KEGGi mgi:Mflv_2296.
PATRICi 18032709. VBIMycGil17082_2348.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi IRNTIND.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci MGIL350054:GHK8-2318-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PYR-GCK.

Entry informationi

Entry nameiSYR_MYCGI
AccessioniPrimary (citable) accession number: A4T8M4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3