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A4T6W8 (G6PI_MYCGI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Mflv_1857
OrganismMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]
Taxonomic identifier350054 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000081243

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5101 By similarity

Sequences

Sequence LengthMass (Da)Tools
A4T6W8 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 0CAF911F567217AD

FASTA54959,375
        10         20         30         40         50         60 
MGTDITATSE WQALARHRDE IGETNLRQLF ADDAARGLRF AVTVGGLYID YSKHRVTAET 

        70         80         90        100        110        120 
LNLLVDVARA AGLETKRDAM FSGEHINTSE DRAVLHTALR LPRDAALTVD GQDVVADVHE 

       130        140        150        160        170        180 
VLDRMGDFTD RLRSGDWLGA TGERITTVVN IGIGGSDLGP VMVDQALRHY ADAGISARFV 

       190        200        210        220        230        240 
SNVDPADLVA KLAGLNPATT LFVIASKTFS TLETLTNATA ARRWLIEALG EDAVSKHFVA 

       250        260        270        280        290        300 
VSTNAKLVAE FGIDTDNMFG FWDWVGGRYS VDSAIGLSVM AVIGRERFAE FLAGFHLIDE 

       310        320        330        340        350        360 
HFRTAPLEAN APVLLGLIGL WYNNFFGAET RAVLPYSNDL ARFAAYLQQL TMESNGKSVQ 

       370        380        390        400        410        420 
ADGTPVSTAT GEIFWGEPGT NGQHAFYQLL HQGTRLVPAD FIGFSEPTDD LPTADGTGSM 

       430        440        450        460        470        480 
HDLLMSNFFA QTQVLAFGKT ADEISAEGTS PDVVPHKVMP GNRPTTSILA TKLTPSVVGQ 

       490        500        510        520        530        540 
LIALYEHQVF VEGVIWGIDS FDQWGVELGK TQAKALLPVL TDAEPPAAQS DSSTDALVRR 


YRSERGRTA 

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PYR-GCK.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000656 Genomic DNA. Translation: ABP44337.1.
RefSeqYP_001133125.1. NC_009338.1.

3D structure databases

ProteinModelPortalA4T6W8.
SMRA4T6W8. Positions 4-546.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING350054.Mflv_1857.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP44337; ABP44337; Mflv_1857.
GeneID4973181.
KEGGmgi:Mflv_1857.
PATRIC18031803. VBIMycGil17082_1899.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMAMIALTHY.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycMGIL350054:GHK8-1875-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_MYCGI
AccessionPrimary (citable) accession number: A4T6W8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: June 11, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways