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A4T6W8

- G6PI_MYCGI

UniProt

A4T6W8 - G6PI_MYCGI

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (15 May 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei353 – 3531Proton donorUniRule annotation
    Active sitei384 – 3841UniRule annotation
    Active sitei510 – 5101UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciMGIL350054:GHK8-1875-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Mflv_1857
    OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
    Taxonomic identifieri350054 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000232: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 549549Glucose-6-phosphate isomerasePRO_1000081243Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi350054.Mflv_1857.

    Structurei

    3D structure databases

    ProteinModelPortaliA4T6W8.
    SMRiA4T6W8. Positions 4-546.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261371.
    KOiK01810.
    OMAiMIALTHY.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4T6W8-1 [UniParc]FASTAAdd to Basket

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    MGTDITATSE WQALARHRDE IGETNLRQLF ADDAARGLRF AVTVGGLYID    50
    YSKHRVTAET LNLLVDVARA AGLETKRDAM FSGEHINTSE DRAVLHTALR 100
    LPRDAALTVD GQDVVADVHE VLDRMGDFTD RLRSGDWLGA TGERITTVVN 150
    IGIGGSDLGP VMVDQALRHY ADAGISARFV SNVDPADLVA KLAGLNPATT 200
    LFVIASKTFS TLETLTNATA ARRWLIEALG EDAVSKHFVA VSTNAKLVAE 250
    FGIDTDNMFG FWDWVGGRYS VDSAIGLSVM AVIGRERFAE FLAGFHLIDE 300
    HFRTAPLEAN APVLLGLIGL WYNNFFGAET RAVLPYSNDL ARFAAYLQQL 350
    TMESNGKSVQ ADGTPVSTAT GEIFWGEPGT NGQHAFYQLL HQGTRLVPAD 400
    FIGFSEPTDD LPTADGTGSM HDLLMSNFFA QTQVLAFGKT ADEISAEGTS 450
    PDVVPHKVMP GNRPTTSILA TKLTPSVVGQ LIALYEHQVF VEGVIWGIDS 500
    FDQWGVELGK TQAKALLPVL TDAEPPAAQS DSSTDALVRR YRSERGRTA 549
    Length:549
    Mass (Da):59,375
    Last modified:May 15, 2007 - v1
    Checksum:i0CAF911F567217AD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000656 Genomic DNA. Translation: ABP44337.1.
    RefSeqiWP_011892748.1. NC_009338.1.
    YP_001133125.1. NC_009338.1.

    Genome annotation databases

    EnsemblBacteriaiABP44337; ABP44337; Mflv_1857.
    GeneIDi4973181.
    KEGGimgi:Mflv_1857.
    PATRICi18031803. VBIMycGil17082_1899.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000656 Genomic DNA. Translation: ABP44337.1 .
    RefSeqi WP_011892748.1. NC_009338.1.
    YP_001133125.1. NC_009338.1.

    3D structure databases

    ProteinModelPortali A4T6W8.
    SMRi A4T6W8. Positions 4-546.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 350054.Mflv_1857.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP44337 ; ABP44337 ; Mflv_1857 .
    GeneIDi 4973181.
    KEGGi mgi:Mflv_1857.
    PATRICi 18031803. VBIMycGil17082_1899.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261371.
    KOi K01810.
    OMAi MIALTHY.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci MGIL350054:GHK8-1875-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PYR-GCK.

    Entry informationi

    Entry nameiG6PI_MYCGI
    AccessioniPrimary (citable) accession number: A4T6W8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: May 15, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3