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A4T6Q2 (A4T6Q2_MYCGI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877

EC=2.1.1.198 HAMAP MF_01877
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877
Gene names
Name:rsmI HAMAP MF_01877
Ordered Locus Names:Mflv_1925
OrganismMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]
Taxonomic identifier350054 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877

Subcellular location

Cytoplasm By similarity HAMAP MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
   Biological processrRNA processing HAMAP MF_01877
   Cellular componentCytoplasm HAMAP MF_01877
   LigandS-adenosyl-L-methionine HAMAP MF_01877
   Molecular functionMethyltransferase HAMAP MF_01877 EMBL ABP44405.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processenzyme-directed rRNA 2'-O-methylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (cytosine-2'-O-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A4T6Q2 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 5F8E39F868F18B46

FASTA27829,464
        10         20         30         40         50         60 
MTAGRLLVGA TPLGQPSDAS ARLVRALGSA DVIAAEDTRR VRTLATALEV KPRGRIVSLY 

        70         80         90        100        110        120 
DQNEASRVPA LLDDIKGGAT VLLVSDAGMP LISDPGYRLV AACAEHDLPV QCLPGPSAVT 

       130        140        150        160        170        180 
TALAVAGLPS ERFCFEGFAP RKQSARATWL RTLSAEPRTC VFFESPRRLA ETLRDAVEVL 

       190        200        210        220        230        240 
GPDRRAVVCR ELTKTHEEIV RGTLGELAEW AAEGVLGEIT VVLDGATPSA DPEALVAEAL 

       250        260        270 
RLVDDGMRVK DACAQVVAGN PGAPPRRALY DAVLRARE 

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PYR-GCK.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000656 Genomic DNA. Translation: ABP44405.1.
RefSeqYP_001133193.1. NC_009338.1.

3D structure databases

ProteinModelPortalA4T6Q2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4T6Q2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000024842; EBMYCP00000024504; EBMYCG00000024837.
GeneID4973249.
GenomeReviewsGene locus Mflv_1925 in contig CP000656_GR.
KEGGmgi:Mflv_1925.
PATRIC18031951. VBIMycGil17082_1972.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0313.
GeneTreeEBGT00050000017256.
HOGENOMHBG529058.
OMAIASDRFC.
PhylomeDBA4T6Q2.
ProtClustDBCLSK725743.

Family and domain databases

HAMAPMF_01877. 16SrRNA_methyltr_I.
[Tree]
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
Gene3DG3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KOK07056.
PANTHERPTHR21091:SF18. PTHR21091:SF18. 1 hit.
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4T6Q2_MYCGI
AccessionPrimary (citable) accession number: A4T6Q2
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)