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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:Mflv_1938
OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Taxonomic identifieri350054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000000232 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000753471 – 192Peptidyl-tRNA hydrolaseAdd BLAST192

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi350054.Mflv_1938

Structurei

3D structure databases

ProteinModelPortaliA4T6N5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004796
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

A4T6N5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEPVLVVGL GNPGPQYATT RHNIGFMVAD VLADRMGETF KVHKKSGAEV
60 70 80 90 100
TTGRLAGRPV VLAKPRVYMN ESGRQVGPLA KFYSIAPTDV VIIHDELDID
110 120 130 140 150
FGRIRLKAGG GVAGHNGLRS VGSALSTNDF QRVRVGIGRP PGQKSGASFV
160 170 180 190
LEPFNSRERP ELGTIIEQAA DATELLIELG IEPAQNTVHA WS
Length:192
Mass (Da):20,520
Last modified:May 15, 2007 - v1
Checksum:i87B12D778203E5DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000656 Genomic DNA Translation: ABP44418.1
RefSeqiWP_011892829.1, NC_009338.1

Genome annotation databases

EnsemblBacteriaiABP44418; ABP44418; Mflv_1938
KEGGimgi:Mflv_1938

Similar proteinsi

Entry informationi

Entry nameiPTH_MYCGI
AccessioniPrimary (citable) accession number: A4T6N5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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