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A4T2V6 (PSD_MYCGI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Mflv_0153
OrganismMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]
Taxonomic identifier350054 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 200200Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000082926
Chain201 – 23232Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000082927

Sites

Site200 – 2012Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2011Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A4T2V6 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: FD92ABCA6DBD3D05

FASTA23224,271
        10         20         30         40         50         60 
MARRPDLKTG PERLAALVRT TVPPMHPAGL PFVGASLAVA LAGRKSRWLR NAGVASAAAN 

        70         80         90        100        110        120 
AAFFRHPPRT PPTRPGVVVA PADGLICLIE DELPPAELEL PAVPLPRISI FLSLFDAHVQ 

       130        140        150        160        170        180 
RAPLAGEVVA VEHRPGLFGS AELAAASADN ERNSVVIRSP EGAEVIAVQI AGLLARRIVC 

       190        200        210        220        230 
NVKSGDKVGL GDTYGLIRYG SRLDTYLPAG SDVLVEVGQR AVAGETVLAE LP

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PYR-GCK.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000656 Genomic DNA. Translation: ABP42648.1.
RefSeqYP_001131436.1. NC_009338.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4T2V6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000026833; EBMYCP00000026495; EBMYCG00000026828.
GeneID4971775.
GenomeReviewsGene locus Mflv_0153 in contig CP000656_GR.
KEGGmgi:Mflv_0153.
PATRIC18028286. VBIMycGil17082_0157.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
GeneTreeEBGT00050000017584.
HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycMGIL350054:MFLV_0153-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_MYCGI
AccessionPrimary (citable) accession number: A4T2V6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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