Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase [Cu-Zn]

Gene

Mflv_0172

Organism
Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mflv_0172Imported
OrganismiMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK))Imported
Taxonomic identifieri350054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000232 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_500267288830 – 236Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST207

Interactioni

Protein-protein interaction databases

STRINGi350054.Mflv_0172

Structurei

3D structure databases

ProteinModelPortaliA4T2T9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 233Sod_CuInterPro annotationAdd BLAST153

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiCOG2032 LUCA
HOGENOMiHOG000263448
KOiK04565
OMAiHADADNF
OrthoDBiPOG091H05EB

Family and domain databases

CDDicd00305 Cu-Zn_Superoxide_Dismutase, 1 hit
Gene3Di2.60.40.200, 1 hit
InterProiView protein in InterPro
IPR036423 SOD-like_Cu/Zn_dom_sf
IPR024134 SOD_Cu/Zn_/chaperone
IPR018152 SOD_Cu/Zn_BS
IPR001424 SOD_Cu_Zn_dom
PANTHERiPTHR10003 PTHR10003, 1 hit
PfamiView protein in Pfam
PF00080 Sod_Cu, 1 hit
SUPFAMiSSF49329 SSF49329, 1 hit
PROSITEiView protein in PROSITE
PS00332 SOD_CU_ZN_2, 1 hit

Sequencei

Sequence statusi: Complete.

A4T2T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRSVAAATL FAVPALALSA CSPPGEVPSD SPGTTPSVWT GSPSPSAEAG
60 70 80 90 100
EHGAGHGGGS GQASGETLTA ELNLADGTTV ANAEIVFSDG YATVTVETTG
110 120 130 140 150
EGDLTPGFHG MHIHQVGKCE PNSVAPTGGA PGNFNSAGGH LQVGGNTGHP
160 170 180 190 200
ASGDLTSLQV REDGSAKVVT TTDAFTAEDL TGDAGTAIII HEKADNFANI
210 220 230
PPERYQQVDG APPPDQTTLA TGDAGARVAC GVITGS
Length:236
Mass (Da):23,240
Last modified:May 15, 2007 - v1
Checksum:i79BF8C99DF7E2AA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000656 Genomic DNA Translation: ABP42667.1
RefSeqiWP_011891174.1, NC_009338.1

Genome annotation databases

EnsemblBacteriaiABP42667; ABP42667; Mflv_0172
KEGGimgi:Mflv_0172

Similar proteinsi

Entry informationi

Entry nameiA4T2T9_MYCGI
AccessioniPrimary (citable) accession number: A4T2T9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: April 25, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health