Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4T2D9 (A4T2D9_MYCGI) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
EC=1.8.4.8 HAMAP MF_00063
Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP MF_00063
PAPS reductase, thioredoxin dependent HAMAP MF_00063
PAPS sulfotransferase HAMAP MF_00063
PAdoPS reductase HAMAP MF_00063
Gene names
Name:cysH HAMAP MF_00063
Ordered Locus Names:Mflv_2685
OrganismMycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) [Complete proteome] [HAMAP]
Taxonomic identifier350054 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length240 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite By similarity. HAMAP MF_00063 SAAS SAAS002500

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 SAAS SAAS002500

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 SAAS SAAS002500

Subcellular location

Cytoplasm By similarity HAMAP MF_00063 SAAS SAAS002500.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily. HAMAP MF_00063

Sequences

Sequence LengthMass (Da)Tools
A4T2D9 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: D481C3DD8678BED3

FASTA24026,159
        10         20         30         40         50         60 
MTDTMSETDL QELAERGAAE LGEHATAQDL LRWTDENFGP ASGRGDYIVA SNMQDAVLVD 

        70         80         90        100        110        120 
LAAKVRPGVD VLFLDTGYHF VETIGTRDAV EAVYDVNVVN VRPEHSVTEQ DAMLGRNLFE 

       130        140        150        160        170        180 
RNANECCRLR KVVPLSKALS GYSAWVTGIR RVEAPTRANA PLISWDKAFG LVKINPLAAW 

       190        200        210        220        230        240 
SDDDMQDYID ANGILVNPLV DEGYPSIGCA PCTHKPVEGA DPRSGRWLGQ SKTECGLHAS

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PYR-GCK.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000656 Genomic DNA. Translation: ABP45162.1.
RefSeqYP_001133950.1. NC_009338.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4T2D9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000022365; EBMYCP00000022027; EBMYCG00000022360.
GeneID4974006.
GenomeReviewsGene locus Mflv_2685 in contig CP000656_GR.
KEGGmgi:Mflv_2685.
PATRIC18033521. VBIMycGil17082_2745.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0175.
GeneTreeEBGT00050000017137.
HOGENOMHBG758022.
OMAFEETLAY.
PhylomeDBA4T2D9.
ProtClustDBPRK02090.

Family and domain databases

HAMAPMF_00063. CysH.
[Tree]
InterProIPR011798. APS_reductase.
IPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00390.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsTIGR02055. APS_reductase. 1 hit.
TIGR00434. CysH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4T2D9_MYCGI
AccessionPrimary (citable) accession number: A4T2D9
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info