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A4SZS0 (A4SZS0_POLSQ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Pnuc_1771
OrganismPolynucleobacter sp. (strain QLW-P1DMWA-1) [Complete proteome] [HAMAP] EMBL ABP34984.1
Taxonomic identifier312153 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Polynucleobacter

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Ontologies

Keywords
   Biological processHeme biosynthesis HAMAP MF_00323
Porphyrin biosynthesis HAMAP MF_00323
   Cellular componentCytoplasm HAMAP MF_00323
   LigandIron HAMAP MF_00323
Metal-binding HAMAP MF_00323
   Molecular functionLyase HAMAP MF_00323 EMBL ABP34984.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processheme biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionferrochelatase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2101Iron By similarity HAMAP MF_00323
Metal binding2911Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A4SZS0 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 6062241D82FA8E76

FASTA36441,170
        10         20         30         40         50         60 
MNQNPHLRTS KTAILLLNLG TPSAPTPKAV RAYLKEFLSD PRVVEIPRII WWCILNGIIL 

        70         80         90        100        110        120 
PIRSGASAKK YASIWLPKLG SPLMHYSRLQ AKELGEKFSQ QGHTVLVDLA MRYGQPSTQE 

       130        140        150        160        170        180 
ALNGLKAQGM ERLLVLPLYP QYSATTTASS FDEVFRVLGT WRDQPELRLV KHYHDNPAYI 

       190        200        210        220        230        240 
AALRDQVLSS WDKNGRPDFA KGDRFVMSFH GLPKRNLMKG DPYHCECLKT GRLLGESLGL 

       250        260        270        280        290        300 
EPGQYIVTFQ SRFGKAEWLK PYTASTIEKL AKEGCQRMDI FCPGFPADCL ETLEEIAMEA 

       310        320        330        340        350        360 
CETFLEHGGK DYRYIPCLNS NPQWIEALSD IAHDHLHGWP LGVESESDLA KRNERAELVE 


RTKS

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References

[1]"Complete sequence of Polynucleobacter sp. QLW-P1DMWA-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Poeckl M., Wu Q.L., Hahn M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: QLW-P1DMWA-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000655 Genomic DNA. Translation: ABP34984.1.
RefSeqYP_001156548.1. NC_009379.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4SZS0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5052437.
GenomeReviewsGene locus Pnuc_1771 in contig CP000655_GR.
KEGGpnu:Pnuc_1771.
PATRIC22968067. VBIPolNec12025_1839.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBA4SZS0.
ProtClustDBPRK00035.

Enzyme and pathway databases

BioCycPSP312153:PNUC_1771-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4SZS0_POLSQ
AccessionPrimary (citable) accession number: A4SZS0
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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