A4SXE8 (A4SXE8_POLSQ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056

Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HAMAP MF_00056
KDO-8-phosphate synthase HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase HAMAP MF_00056

Gene names

Name:	kdsA HAMAP MF_00056
Ordered Locus Names:	Pnuc_0946

Organism

Polynucleobacter sp. (strain QLW-P1DMWA-1) [Complete proteome] [HAMAP] EMBL ABP34162.1

Taxonomic identifier

312153 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Polynucleobacter

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056
Pathway	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056 Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056
Subcellular location	Cytoplasm By similarity HAMAP MF_00056.
Sequence similarities	Belongs to the KdsA family. HAMAP MF_00056

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis HAMAP MF_00056
Cellular component	Cytoplasm HAMAP MF_00056
Molecular function	Transferase HAMAP MF_00056
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-deoxy-8-phosphooctulonate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SXE8 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 022B6840F7E81964	FASTA	287	30,838
	10 20 30 40 50 60 MSTFKLCGFD VGLDHRFFLI AGPCVIESEQ SAIDIAGELK EITSALKIPF IYKSSFDKAN 70 80 90 100 110 120 RSSGTSFRGL GMEKGLEILA KVKKEVGVPV LTDVHDIGEI AAVAKVVDVL QTPAFLCRQT 130 140 150 160 170 180 DFIRACAQSG KPVNFKKGQF LSPHEMLNVI EKARGAAAEM GLSDQFMVCE RGASFGYNNL 190 200 210 220 230 240 VSDMRSLAIL RESKAPVVFD ATHSVQLPGG QGNSSGGQRE FVPVLARAAV AVGISGLFME 250 260 270 280 THPDPAKALS DGPNAVPLNR MKELLQSLVD IDSVVKANNS FLEDSFK

References

[1]

"Complete sequence of Polynucleobacter sp. QLW-P1DMWA-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Poeckl M., Wu Q.L., Hahn M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: QLW-P1DMWA-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000655 Genomic DNA. Translation: ABP34162.1.
RefSeq	YP_001155726.1. NC_009379.1.
3D structure databases
ProteinModelPortal	A4SXE8.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SXE8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5053091.
GenomeReviews	Gene locus Pnuc_0946 in contig CP000655_GR.
KEGG	pnu:Pnuc_0946.
PATRIC	22966317. VBIPolNec12025_0978.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2877.
HOGENOM	HBG575990.
OMA	HENEQCA.
PhylomeDB	A4SXE8.
ProtClustDB	PRK05198.
Enzyme and pathway databases
BioCyc	PSP312153:PNUC_0946-MONOMER.
Family and domain databases
HAMAP	MF_00056. KDO8P_synth. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006269. KDO8P_synthase. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01627.
PANTHER	PTHR21057:SF2. KDO8P_synthase. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01362. KDO8P_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4SXE8_POLSQ

Accession

Primary (citable) accession number: A4SXE8

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)