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A4STE1

- G6PI_AERS4

UniProt

A4STE1 - G6PI_AERS4

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, ASA_4235
Organism
Aeromonas salmonicida (strain A449)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donor By similarity
Active sitei386 – 3861 By similarity
Active sitei514 – 5141 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciASAL382245:GJJN-4221-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:ASA_4235
OrganismiAeromonas salmonicida (strain A449)
Taxonomic identifieri382245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
ProteomesiUP000000225: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomeraseUniRule annotationPRO_1000013938Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi382245.ASA_4235.

Structurei

3D structure databases

ProteinModelPortaliA4STE1.
SMRiA4STE1. Positions 10-542.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4STE1-1 [UniParc]FASTAAdd to Basket

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MKNINPTQTQ AWQALEAHFA ANKETRLKDL FAQDPKRFDK FSLTFGGDIL    50
VDYSKNLITE ETLKLLVDLA KETDLRSAID AMFNGEKINM TEGRSVLHVA 100
LRNRSDRPIE CDGKDVMPEV NAVLAKMKGF CEKIISGEWK GYTGKAIQHV 150
VNIGIGGSDL GPVMITEALR PYKNHLQMHF VSNVDGTHIA ETLKEIDAET 200
TLFLVASKTF TTQETMTNAL TARDWFIKIA GDKAHVAKHF AALSTNGKAV 250
AEFGIDTDNM FEFWDWVGGR YSSWSAIGMP IALSVGFDNF EALLQGAFEM 300
DMHFATASYE QNVPVLLALI GLWYNNFHGA ESEAILPYDQ YMHRFPAYFQ 350
QGNMESNGKY VDRNGNPVDH QTGPIIWGEP GTNGQHAFYQ LIHQGTKLIP 400
CDFLAPAISH NPIGDHHPKL LANFFAQTEA LAFGKSKEQV EAEFLAAGKT 450
LEQVEDLVPF KVFEGNRPTN SILFKSLTPK TLGALIAMYE HKIFVQGAIW 500
NIFSFDQWGV ELGKQLANKI LPELNTAEAV TSHDCSTNGL INTWKAWKA 549
Length:549
Mass (Da):61,202
Last modified:May 15, 2007 - v1
Checksum:i65F29B5ED77837F1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000644 Genomic DNA. Translation: ABO92163.1.
RefSeqiYP_001143911.1. NC_009348.1.

Genome annotation databases

EnsemblBacteriaiABO92163; ABO92163; ASA_4235.
GeneIDi4996959.
KEGGiasa:ASA_4235.
PATRICi20794930. VBIAerSal2987_4203.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000644 Genomic DNA. Translation: ABO92163.1 .
RefSeqi YP_001143911.1. NC_009348.1.

3D structure databases

ProteinModelPortali A4STE1.
SMRi A4STE1. Positions 10-542.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 382245.ASA_4235.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO92163 ; ABO92163 ; ASA_4235 .
GeneIDi 4996959.
KEGGi asa:ASA_4235.
PATRICi 20794930. VBIAerSal2987_4203.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261371.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci ASAL382245:GJJN-4221-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
    Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
    BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A449.

Entry informationi

Entry nameiG6PI_AERS4
AccessioniPrimary (citable) accession number: A4STE1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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