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Reviewed, UniProtKB/Swiss-Prot A4ST50 (HEM6_AERS4)

Last modified November 3, 2009. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: ASA_4133
OrganismAeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]
Taxonomic identifier382245 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

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Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333
PRO_1000019456

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Sequences

Sequence LengthMass (Da)Tools
A4ST50-1 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 54EF7632B55F89C1

FASTA30234,914
        10         20         30         40         50         60 
MSKPDVAQVK AFLLQLQDEI CRSLEQADGV GRFVEDAWAR EGGGGGRTRV MRHGDMIEQG 

        70         80         90        100        110        120 
GVNFSHVYGD AMPASATAHR PELAGRKFEA MGVSLVIHPH NPYVPTSHAN VRFFIAEKEG 

       130        140        150        160        170        180 
EEPIWWFGGG FDLTPFYPFA EDVQHWHRVS RDLCQPFGED IYPEFKSWCD RYFFLKHRNE 

       190        200        210        220        230        240 
TRGVGGLFFD DLNRWPFADC FAFMQAVGRG YLDAYLPIIE RRKAQPYGER EREFQLYRRG 

       250        260        270        280        290        300 
RYVEFNLVYD RGTLFGLQTG GRTESILMSM PPLARWEYDW QPEAGSPEAL LYTDYLAPRE 


WL

« Hide

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References

[1]"The genome sequence of Aeromonas salmonicida subsp. salmonicida A449."
Reith M.E., Singh R.K., Curtis B., Boyd J., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J., Johnson S., Brown L.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000644 Genomic DNA. Translation: ABO92072.1.
RefSeqYP_001143820.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4ST50.

Genome annotation databases

GeneID4997266.
GenomeReviewsGene locus ASA_4133 in contig CP000644_GR.
KEGGasa:ASA_4133.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVKAYLLD.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_AERS4
AccessionPrimary (citable) accession number: A4ST50
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents