A4SSF6 (A4SSF6_AERS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenylate cyclase RuleBase RU000604
EC=4.6.1.1 RuleBase RU000604

Gene names

Name:	cyaA EMBL ABO91828.1
Ordered Locus Names:	ASA_3874

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	843 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP = 3',5'-cyclic AMP + diphosphate. RuleBase RU000604
Subcellular location	Cytoplasm By similarity RuleBase RU000604.
Sequence similarities	Belongs to the adenylyl cyclase class-1 family. RuleBase RU004184

Ontologies

Keywords
Biological process	cAMP biosynthesis RuleBase RU000604
Molecular function	Lyase RuleBase RU000604
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	adenylate cyclase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SSF6 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 44BE7720FBA5117B	FASTA	843	96,965
	10 20 30 40 50 60 MLVKLDTLVA RYDELNRLKT QRALGLMSRY GQQVFQLLPV MLHFNHPLLP GYVAGDVPHG 70 80 90 100 110 120 IWSFTANEAQ QAFIQDLCQN ANCQNGLTTH DKSIQGLYSM GSTSSIGQCC HSDLDIWVCH 130 140 150 160 170 180 VAGLSQARLE LLDLKCQQLS KWAEQRGVDL NFFLIPEDKF RQCNDAQMQG ESCGSAQHLL 190 200 210 220 230 240 LLDEFYLSAM LIAGKRLLWY LVPAEYDDHY DEYVDSLFAD GKLSQDDWLD LGGFNRIPAE 250 260 270 280 290 300 EYFGSALWQL YKGIDSPYKA VLKSVLMEAY SHEYPNTRLL SVTSRDWFQH NDGMHYRLDN 310 320 330 340 350 360 YCLMLDKVTN YLKSIGDMQR LDLVRRCFYL KVCDGLSHPK EEHSPAWRRE QMTQLVSYWG 370 380 390 400 410 420 WSPERLHHLD HRQEWKVEDV KVAHAELLEA LMQSYRNLIQ FARRNNISES INPEDIGILS 430 440 450 460 470 480 RKLYAAFESL PGKVQRINLT IAPDLSEQDL SLVQVPHGRL NRAGWYLYKH SLDPVDIIGR 490 500 510 520 530 540 APLEYNGYIS KLVSWAYFNG LLTPQSRVHL FNQGSDLHID NLHQFCRDLS GTFPVKYPRA 550 560 570 580 590 600 TNLALSRPCE IRQLSIFLNL ETDPTSHWMG QVIEFDANAA DVFSFGRNQE CLVGSVDLVY 610 620 630 640 650 660 RNSWSEIRTL HFQGDEAVVD ALTTILGKMH QDAAAPEMIE VFCYSQHFRS LIRTRFQQLV 670 680 690 700 710 720 AECIELRLAR DKLQLVKTLA LGREKYGIFF ERRGVSVKKL ENAIDFYRHI SHNKLDHLPL 730 740 750 760 770 780 RLDKTHSQHL PDIVDAYASE GLVQFFFDTR DAGTNIYILD EANRVEIYQH FAGNKNELVQ 790 800 810 820 830 840 GVNRFYASSH ERFSDAGQFS NFNLPQYYEI VQINGELEVI PYRSQGQMRD NASPAHELGS ATG

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO91828.1.
RefSeq	YP_001143576.1. NC_009348.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4SSF6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4998010.
GenomeReviews	Gene locus ASA_3874 in contig CP000644_GR.
KEGG	asa:ASA_3874.
PATRIC	20794180. VBIAerSal2987_3840.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3072.
HOGENOM	HBG678054.
OMA	LWQLYKG.
PhylomeDB	A4SSF6.
ProtClustDB	PRK09450.
Family and domain databases
InterPro	IPR000274. Adenylate_cyclase_1. IPR024686. Adenylate_cyclase_1_CS. IPR024685. Adenylate_cyclase_1_N. [Graphical view]
KO	K05851.
Pfam	PF12633. Adenyl_cycl_N. 1 hit. PF01295. Adenylate_cycl. 1 hit. [Graphical view]
PIRSF	PIRSF001444. Adenylate_cycl. 1 hit.
PROSITE	PS01092. ADENYLATE_CYCLASE_1_1. 1 hit. PS01093. ADENYLATE_CYCLASE_1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4SSF6_AERS4

Accession

Primary (citable) accession number: A4SSF6

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)