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A4SSF6

- A4SSF6_AERS4

UniProt

A4SSF6 - A4SSF6_AERS4

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Protein
Adenylate cyclase
Gene
cyaA, ASA_3874
Organism
Aeromonas salmonicida (strain A449)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.

GO - Molecular functioni

  1. adenylate cyclase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Biological processi

    cAMP biosynthesisUniRule annotation

    Enzyme and pathway databases

    BioCyciASAL382245:GJJN-3861-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Adenylate cyclaseUniRule annotation (EC:4.6.1.1UniRule annotation)
    Gene namesi
    Name:cyaAImported
    Ordered Locus Names:ASA_3874Imported
    OrganismiAeromonas salmonicida (strain A449)Imported
    Taxonomic identifieri382245 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
    ProteomesiUP000000225: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Interactioni

    Protein-protein interaction databases

    STRINGi382245.ASA_3874.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the adenylyl cyclase class-1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3072.
    HOGENOMiHOG000270910.
    KOiK05851.
    OMAiSEGFLQF.
    OrthoDBiEOG63JR9H.

    Family and domain databases

    InterProiIPR000274. Adenylate_cyclase_1.
    IPR024686. Adenylate_cyclase_1_CS.
    IPR024685. Adenylate_cyclase_1_N.
    [Graphical view]
    PfamiPF12633. Adenyl_cycl_N. 1 hit.
    PF01295. Adenylate_cycl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
    PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
    PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4SSF6-1 [UniParc]FASTAAdd to Basket

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    MLVKLDTLVA RYDELNRLKT QRALGLMSRY GQQVFQLLPV MLHFNHPLLP    50
    GYVAGDVPHG IWSFTANEAQ QAFIQDLCQN ANCQNGLTTH DKSIQGLYSM 100
    GSTSSIGQCC HSDLDIWVCH VAGLSQARLE LLDLKCQQLS KWAEQRGVDL 150
    NFFLIPEDKF RQCNDAQMQG ESCGSAQHLL LLDEFYLSAM LIAGKRLLWY 200
    LVPAEYDDHY DEYVDSLFAD GKLSQDDWLD LGGFNRIPAE EYFGSALWQL 250
    YKGIDSPYKA VLKSVLMEAY SHEYPNTRLL SVTSRDWFQH NDGMHYRLDN 300
    YCLMLDKVTN YLKSIGDMQR LDLVRRCFYL KVCDGLSHPK EEHSPAWRRE 350
    QMTQLVSYWG WSPERLHHLD HRQEWKVEDV KVAHAELLEA LMQSYRNLIQ 400
    FARRNNISES INPEDIGILS RKLYAAFESL PGKVQRINLT IAPDLSEQDL 450
    SLVQVPHGRL NRAGWYLYKH SLDPVDIIGR APLEYNGYIS KLVSWAYFNG 500
    LLTPQSRVHL FNQGSDLHID NLHQFCRDLS GTFPVKYPRA TNLALSRPCE 550
    IRQLSIFLNL ETDPTSHWMG QVIEFDANAA DVFSFGRNQE CLVGSVDLVY 600
    RNSWSEIRTL HFQGDEAVVD ALTTILGKMH QDAAAPEMIE VFCYSQHFRS 650
    LIRTRFQQLV AECIELRLAR DKLQLVKTLA LGREKYGIFF ERRGVSVKKL 700
    ENAIDFYRHI SHNKLDHLPL RLDKTHSQHL PDIVDAYASE GLVQFFFDTR 750
    DAGTNIYILD EANRVEIYQH FAGNKNELVQ GVNRFYASSH ERFSDAGQFS 800
    NFNLPQYYEI VQINGELEVI PYRSQGQMRD NASPAHELGS ATG 843
    Length:843
    Mass (Da):96,965
    Last modified:May 15, 2007 - v1
    Checksum:i44BE7720FBA5117B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000644 Genomic DNA. Translation: ABO91828.1.
    RefSeqiYP_001143576.1. NC_009348.1.

    Genome annotation databases

    EnsemblBacteriaiABO91828; ABO91828; ASA_3874.
    GeneIDi4998010.
    KEGGiasa:ASA_3874.
    PATRICi20794180. VBIAerSal2987_3840.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000644 Genomic DNA. Translation: ABO91828.1 .
    RefSeqi YP_001143576.1. NC_009348.1.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 382245.ASA_3874.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABO91828 ; ABO91828 ; ASA_3874 .
    GeneIDi 4998010.
    KEGGi asa:ASA_3874.
    PATRICi 20794180. VBIAerSal2987_3840.

    Phylogenomic databases

    eggNOGi COG3072.
    HOGENOMi HOG000270910.
    KOi K05851.
    OMAi SEGFLQF.
    OrthoDBi EOG63JR9H.

    Enzyme and pathway databases

    BioCyci ASAL382245:GJJN-3861-MONOMER.

    Family and domain databases

    InterProi IPR000274. Adenylate_cyclase_1.
    IPR024686. Adenylate_cyclase_1_CS.
    IPR024685. Adenylate_cyclase_1_N.
    [Graphical view ]
    Pfami PF12633. Adenyl_cycl_N. 1 hit.
    PF01295. Adenylate_cycl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001444. Adenylate_cycl. 1 hit.
    PROSITEi PS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
    PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
      Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
      BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: A449.

    Entry informationi

    Entry nameiA4SSF6_AERS4
    AccessioniPrimary (citable) accession number: A4SSF6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 15, 2007
    Last sequence update: May 15, 2007
    Last modified: May 14, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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