A4SRJ5 (A4SRJ5_AERS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase 2 HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase 2 HAMAP MF_00020

Gene names

Name:	ackA EMBL ABO91517.1
Synonyms:	ackA2 HAMAP MF_00020
Ordered Locus Names:	ASA_3549

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 RuleBase RU003835 EMBL ABO91517.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SRJ5 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: D329EBB2A88EFAEB	FASTA	399	42,554
	10 20 30 40 50 60 MSKLVLILNC GSSSLKFAVM DAETGEDMLS GLAECFNLDD ARIKWKLHGV KGEAMLGAGA 70 80 90 100 110 120 AHQAALDHIV GHILPQDPTL AEQLVAIGHR IVHGGEQFSR SVRIDDGVIA GIEAAIPFAP 130 140 150 160 170 180 LHNPAHLIGI RAALKVFPQL AEKNVAVFDT AFHQTLPQEA YLYALPYKLY KENGIRRYGA 190 200 210 220 230 240 HGTSHRFIAE ETAKALGKPL AELNIINCHL GNGASVCAIK NGESVDTSMG LTPLEGLAMG 250 260 270 280 290 300 TRSGDIDPAV VFFMHDQLGY SVDEINHTLT RESGLLGLTE VSSDCRYVTS NYATDAGAKR 310 320 330 340 350 360 ALDVFTYRVA KYVGAYAAAM EGRLDALVFT GGIGENAAMV REMVLDRLAL FGFKVDKEAN 370 380 390 NAAVLGGEGP ITAEGSRLAL VMPTNEELVI ARDALSLVG

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO91517.1.
RefSeq	YP_001143265.1. NC_009348.1.
3D structure databases
ProteinModelPortal	A4SRJ5.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SRJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4995369.
GenomeReviews	Gene locus ASA_3549 in contig CP000644_GR.
KEGG	asa:ASA_3549.
PATRIC	20793540. VBIAerSal2987_3530.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	FMINEAG.
PhylomeDB	A4SRJ5.
ProtClustDB	CLSK729891.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4SRJ5_AERS4

Accession

Primary (citable) accession number: A4SRJ5

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)