A4SRG9 (CYSD_AERS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	ASA_3523

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340174

Sequences

	Sequence		Length	Mass (Da)
	A4SRG9 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: DF1F746CD10FDF44	FASTA	309	35,710
	10 20 30 40 50 60 MESIRAGVSR ERLTHLQQLE AESIHIIREV AAEFENPVMM YSIGKDSSVM LHLARKAFYP 70 80 90 100 110 120 GKIPFPLLHV DTDWKFKEMI TFRDETAKKY GLDLIVHKNP DGLAMGINPF VHGSGKHTDI 130 140 150 160 170 180 MKTEGLKQAL NQHGFDAAFG GARRDEEKSR AKERVYSFRD KSHRWDPKNQ RPELWRVYNS 190 200 210 220 230 240 QVNKGESIRV FPLSNWTELD IWQYIYLENI DIVPLYFAAV RPVVERNGIK IMVDDERMPI 250 260 270 280 290 300 GPEDEVKQEL VRFRTLGCYP LTGAIESDAT TLPEIIEEML LTTSSERQGR LIDHDQAGSM EQKKRQGYF

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A449.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO91491.1.
RefSeq	YP_001143239.1. NC_009348.1.
3D structure databases
ProteinModelPortal	A4SRG9.
SMR	A4SRG9. Positions 11-219.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SRG9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4995754.
GenomeReviews	Gene locus ASA_3523 in contig CP000644_GR.
KEGG	asa:ASA_3523.
PATRIC	20793500. VBIAerSal2987_3510.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	RVIDHDA.
PhylomeDB	A4SRG9.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	ASAL382245:ASA_3523-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_AERS4

Accession

Primary (citable) accession number: A4SRG9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program