A4SRB1 (GCP_AERS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	ASA_3465

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 337	337	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303248

Sequences

	Sequence		Length	Mass (Da)
	A4SRB1 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: F88BEE9500BD563C	FASTA	337	36,147
	10 20 30 40 50 60 MRVLGIETSC DETGIAIFDD QKGILSHQLY SQVKLHADYG GVVPELASRD HVRKTIPLIQ 70 80 90 100 110 120 AALQEAGLDK DGIDGIAYTA GPGLVGAILV GATIGRSLAM AWNKPAIAVH HMEGHLLAPM 130 140 150 160 170 180 LEERAPEFPF VALLVSGGHS MLVRVDGIGS YQLLGESIDD AAGEAFDKTA KLMGLDYPGG 190 200 210 220 230 240 PLLSRLAEKG TTGRFHFPRP MTDRPGLDMS FSGLKTFAAN TIAANGDDEQ TRADIARAFE 250 260 270 280 290 300 DAVVDTLAIK CRRALKETGL KRLVVAGGVS ANRHLRAQLA ELMESLKGKV FYPRTEYCTD 310 320 330 NGAMIAYAGM QRLKAGVFEP LAVKAVPRWP LDTLDPV

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A449.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO91433.1.
RefSeq	YP_001143181.1. NC_009348.1.
3D structure databases
ProteinModelPortal	A4SRB1.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SRB1.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4995572.
GenomeReviews	Gene locus ASA_3465 in contig CP000644_GR.
KEGG	asa:ASA_3465.
PATRIC	20793386. VBIAerSal2987_3453.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PAVGVHH.
PhylomeDB	A4SRB1.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	ASAL382245:ASA_3465-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_AERS4

Accession

Primary (citable) accession number: A4SRB1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program