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A4SQ68 (A4SQ68_AERS4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Homoserine kinase EMBL ABO91040.1
Gene names
Name:thrB EMBL ABO91040.1
Ordered Locus Names:ASA_3039
OrganismAeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]
Taxonomic identifier382245 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate By similarity. SAAS SAAS006203

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. SAAS SAAS006203

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. SAAS SAAS006203

Subcellular location

Cytoplasm By similarity SAAS SAAS006203.

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Sequences

Sequence LengthMass (Da)Tools
A4SQ68 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 4FE8AFD4D587B827

FASTA32234,185
        10         20         30         40         50         60 
MAQGGSVVAY APASSANLSV GFDVLGAALA PVDGSLLGDR VQVKAADVAF ALSSVGRYAH 

        70         80         90        100        110        120 
KLPDDPKKNI LYDCWVAYGE ALEKRGLTMQ PLEMVLEKNL PVGSGLGSSA CSVVAALEGL 

       130        140        150        160        170        180 
NAFHGAPLNE HDMLLLMGEM EGRISGSVHY DNVAPCYLGG MQLVLEEHGV ISQGIPVFEQ 

       190        200        210        220        230        240 
WYWVVCYPGT VVSTAAARAI LPAQYRRQDC LTYGRRLAAF VHASYTGQEG LAASVLKDVI 

       250        260        270        280        290        300 
AEPYRAALIE GFNEVRAQAA QNGALATGIS GSGPSVFVVM KDLAQAERMK DWMDAHFVQN 

       310        320 
EDGFARVCKL DMAGARVTGS EL

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References

[1]"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000644 Genomic DNA. Translation: ABO91040.1.
RefSeqYP_001142788.1. NC_009348.1.

3D structure databases

ProteinModelPortalA4SQ68.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4SQ68.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4995716.
GenomeReviewsGene locus ASA_3039 in contig CP000644_GR.
KEGGasa:ASA_3039.
PATRIC20792485. VBIAerSal2987_3017.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0083.
HOGENOMHBG646290.
OMAGSAHADN.
PhylomeDBA4SQ68.
ProtClustDBPRK01212.

Family and domain databases

InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR000870. Homoserine_kinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00872.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000676. Homoser_kin. 1 hit.
PRINTSPR00958. HOMSERKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00191. ThrB. 1 hit.
PROSITEPS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4SQ68_AERS4
AccessionPrimary (citable) accession number: A4SQ68
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info