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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

gabT

Organism
Aeromonas salmonicida (strain A449)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciASAL382245:GJJN-3008-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported
Gene namesi
Name:gabTImported
Ordered Locus Names:ASA_3021Imported
OrganismiAeromonas salmonicida (strain A449)Imported
Taxonomic identifieri382245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
ProteomesiUP000000225: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi382245.ASA_3021.

Structurei

3D structure databases

ProteinModelPortaliA4SQ50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiPEGNHYL.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4SQ50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHSDSHADN NRAWQARGEA AVVNGVGTLL PVFIDKTLNA ELWDVEGNRY
60 70 80 90 100
IDFASGIAVL NTGHNHPKVV AAVREQLEKF SHTCFQVTPY PGYIELAEKL
110 120 130 140 150
NALVPGPTPK RTLFLSTGAE AVENAIKIAR AHTGRSGTIA FKGGFHGRTM
160 170 180 190 200
MGMALTGKVV PYKTGFGPFP GEVYHLPFPS DYLGVSEADA LAALDLCFSS
210 220 230 240 250
DIEPARVAAI ILEPVQGEGG FYSASPSFMQ SLRKLCDQHG IVLICDEIQS
260 270 280 290 300
GFCRTGKTFA TEYSGIEPDI MTLAKSLAGG FPLSAVVGKA AIMNAAKPGG
310 320 330 340 350
LGGTYAGSPI ACAAALAVLE VIEEEQLNQK ALAQGAQIKA RLHQLAEGFD
360 370 380 390 400
CIGDIRGPGA MVAMELVKGR DASQPDPDLT KRLVAEAGKR GLVLLSCGVR
410 420 430
ANVIRFLAPL TATPALIEEG LALLEQALTA ASQG
Length:434
Mass (Da):45,698
Last modified:May 15, 2007 - v1
Checksum:iE663BE9F78EA9FCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO91022.1.
RefSeqiYP_001142770.1. NC_009348.1.

Genome annotation databases

EnsemblBacteriaiABO91022; ABO91022; ASA_3021.
GeneIDi4996444.
KEGGiasa:ASA_3021.
PATRICi20792453. VBIAerSal2987_3001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO91022.1.
RefSeqiYP_001142770.1. NC_009348.1.

3D structure databases

ProteinModelPortaliA4SQ50.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi382245.ASA_3021.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO91022; ABO91022; ASA_3021.
GeneIDi4996444.
KEGGiasa:ASA_3021.
PATRICi20792453. VBIAerSal2987_3001.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiPEGNHYL.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciASAL382245:GJJN-3008-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
    Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
    BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A449Imported.

Entry informationi

Entry nameiA4SQ50_AERS4
AccessioniPrimary (citable) accession number: A4SQ50
Entry historyi
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 7, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.