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Protein

Probable D-serine dehydratase

Gene

dsdA

Organism
Aeromonas salmonicida (strain A449)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:ASA_2940
OrganismiAeromonas salmonicida (strain A449)
Taxonomic identifieri382245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000225 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000637071 – 443Probable D-serine dehydrataseAdd BLAST443

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei118N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi382245.ASA_2940.

Structurei

3D structure databases

ProteinModelPortaliA4SPX2.
SMRiA4SPX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
KOiK01753.
OMAiESDPNCF.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat. 1 hit.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 3 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4SPX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNIDVQQLT NQFPLVQSLI ALEPVTWFNP KASTLAVGLP YVGLDGSDVA
60 70 80 90 100
DASARLARFA PYMCEAFPET RASKGILESE IVAIPAMQAT LNTRYGVEVT
110 120 130 140 150
GKLLLKKDSH LPISGSIKAR GGIYEVLTHA EQLAIKAGLL CEEDDYRKLF
160 170 180 190 200
SEEFRQFFGQ YSIAVGSTGN LGMSIGIMSA KLGFTVTVHM SADAREWKKR
210 220 230 240 250
KLREHGVIVV EYAEDYGVAV EQGRKEAERD PNCFFIDDEN SRTLFLGYSV
260 270 280 290 300
AGERVKTQFD QMGIKVDAEH PLFVYLPCGV GGGPGGVAFG LKLAFGDNVH
310 320 330 340 350
CLFAEPTHSP CMLLGVHTGL HDQISVQDLG IDNLTAADGL AVGRASGFVG
360 370 380 390 400
RAMERLLDGF YTLSDQEMYD LLGLLARDEQ IKLEPSALAG MPGPWRIAAD
410 420 430 440
REWQTERGFD AATLARATHL VWATGGGMVP AEEMEKYLAT AEI
Length:443
Mass (Da):48,247
Last modified:May 15, 2007 - v1
Checksum:i9465B6D03C7F8A25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO90944.1.
RefSeqiWP_005312755.1. NC_009348.1.

Genome annotation databases

EnsemblBacteriaiABO90944; ABO90944; ASA_2940.
GeneIDi4994610.
KEGGiasa:ASA_2940.
PATRICi20792295. VBIAerSal2987_2922.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO90944.1.
RefSeqiWP_005312755.1. NC_009348.1.

3D structure databases

ProteinModelPortaliA4SPX2.
SMRiA4SPX2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi382245.ASA_2940.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO90944; ABO90944; ASA_2940.
GeneIDi4994610.
KEGGiasa:ASA_2940.
PATRICi20792295. VBIAerSal2987_2922.

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
KOiK01753.
OMAiESDPNCF.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat. 1 hit.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 3 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSDHD_AERS4
AccessioniPrimary (citable) accession number: A4SPX2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 15, 2007
Last modified: November 2, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.