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A4SNF4 (A4SNF4_AERS4) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Beta-galactosidase PIRNR PIRNR001084

Short name=Beta-gal PIRNR PIRNR001084
EC=3.2.1.23 PIRNR PIRNR001084
Gene names
Ordered Locus Names:ASA_2378
OrganismAeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]
Taxonomic identifier382245 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas

Protein attributes

Sequence length686 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. PIRNR PIRNR001084

Sequence similarities

Belongs to the glycosyl hydrolase 42 family. PIRNR PIRNR001084

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1571Proton donor By similarity PIRSR PIRSR001084-1
Active site3141Nucleophile By similarity PIRSR PIRSR001084-1
Metal binding1221Zinc By similarity PIRSR PIRSR001084-3
Metal binding1621Zinc By similarity PIRSR PIRSR001084-3
Metal binding1641Zinc By similarity PIRSR PIRSR001084-3
Metal binding1671Zinc By similarity PIRSR PIRSR001084-3
Binding site1181Substrate By similarity PIRSR PIRSR001084-2
Binding site1561Substrate By similarity PIRSR PIRSR001084-2
Binding site3221Substrate By similarity PIRSR PIRSR001084-2

Sequences

Sequence LengthMass (Da)Tools
A4SNF4 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 5BAB08284A60D73A

FASTA68677,205
        10         20         30         40         50         60 
MFKFPPLSSK VPVLLHGADY NPDQWLDDPA VLAKDIEMMK QTNSNVMSVG IFSWSGLEPE 

        70         80         90        100        110        120 
EGRYEFGWLD QVLDTLYANG IYTFLATPSG ARPAWLSKAY PEVLRTDKNR VKALHGGRHN 

       130        140        150        160        170        180 
HCMSSPVYRD KVRQINGALA KRYANHPGVI AWHISNEYGG ECHCELCQHQ FRDWLKARYG 

       190        200        210        220        230        240 
TLDALNKAWW STFWSHTFTD WQQIESPSPI GESTIHGLNL DWKRFNTAQV SDFCPAEIAP 

       250        260        270        280        290        300 
LKAENPALPA TTNFMEYFYD YDYWQLAKVI DFISWDSYPL WHNAEDDCTL AAYTAMYHDL 

       310        320        330        340        350        360 
MRTLKGGKPF YLMESTPSLT NWQPISKLKK PGMHILSSLQ AVAHGSDSVQ YFQWRKSRGS 

       370        380        390        400        410        420 
VEKFHGAVVD HVGHIDTRVG REVQALGETL SKISAVAGSK VEARVAIIFD WESRWAMDNA 

       430        440        450        460        470        480 
QGPRNAGLFY EKTVAEHYRA FWEQGVAVDV INADCDLSPY SLVIAPMLYM VRDGFAERVD 

       490        500        510        520        530        540 
GFVQAGGRFV TTYWSGIVNE TDLCHLGGFP GPLRPVLGIW AEEIDSLYDH ERNAISGLPD 

       550        560        570        580        590        600 
NELGLKGPYE VTQLCDLIQL EGARALASYD SDFYAGRPAV TVNDHGKGQA YYIASRNDLA 

       610        620        630        640        650        660 
FQRDFFGKLI EELGLPRALA TELPSGVTAQ RRTDGEQEFI FLQNYTCEAR AVLLPSAYTE 

       670        680 
MSTGQPLTGK LALEAYGCRV LSRPVQ 

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References

[1]"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000644 Genomic DNA. Translation: ABO90426.1.
RefSeqYP_001142174.1. NC_009348.1.

3D structure databases

ProteinModelPortalA4SNF4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4SNF4.

Protein family/group databases

CAZyGH42. Glycoside Hydrolase Family 42.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4997278.
GenomeReviewsGene locus ASA_2378 in contig CP000644_GR.
KEGGasa:ASA_2378.
PATRIC20791102. VBIAerSal2987_2335.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1874.
HOGENOMHBG476453.
OMAHGSDTVQ.
ProtClustDBCLSK888649.

Family and domain databases

InterProIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
Gene3DG3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KOK12308.
PfamPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFPIRSF001084. B-galactosidase. 1 hit.
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4SNF4_AERS4
AccessionPrimary (citable) accession number: A4SNF4
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)