A4SNB0 (DADA_AERS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	ASA_2333

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	417 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 417	417	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000066068
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	A4SNB0 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: EA3E4B79746C655A	FASTA	417	44,847
	10 20 30 40 50 60 MDIVVLGGGV VGVTSAWYLA KAGHKVTLLE RRDGVALETS HANAGQISPG YAAPWAAPGI 70 80 90 100 110 120 PLKAAKWLLQ KHAPFTVRPT SDPFQLRWML KMFANCTPAA YATNKGRMVR LAEYSRDCMK 130 140 150 160 170 180 TLRDELALDY EGRQLGTLQL FRSQAQLDAS KRDIEVLEEY GVPYQSLDAS GCEGVEPALA 190 200 210 220 230 240 RVRGKIVGGL RLPGDETGDC FRFTKALAAE AQKLGVEFVF NCAIDEIELS LGRAVAVRAG 250 260 270 280 290 300 EQRFKADAIV CALGSYATGF LRPLGIDLPV YPVKGYSLTL PMTDADAVPR STVLDETYKV 310 320 330 340 350 360 AITRFNERIR VGGMAELSGF NLALNPKRYD TLAMVVGDLF PEGGDISRAE FWTGLRPMTP 370 380 390 400 410 DGTPLVGPSP VPGLWLNTGH GTLGWTMAAG SGQLLSDLIS GSSTAISDEG LTLARYG

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A449.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO90382.1.
RefSeq	YP_001142130.1. NC_009348.1.
3D structure databases
ProteinModelPortal	A4SNB0.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SNB0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4995089.
GenomeReviews	Gene locus ASA_2333 in contig CP000644_GR.
KEGG	asa:ASA_2333.
PATRIC	20791006. VBIAerSal2987_2287.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0665.
HOGENOM	HBG729204.
OMA	NCTAAHY.
PhylomeDB	A4SNB0.
ProtClustDB	CLSK729218.
Enzyme and pathway databases
BioCyc	ASAL382245:ASA_2333-MONOMER.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_AERS4

Accession

Primary (citable) accession number: A4SNB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program