A4SN67 (A4SN67_AERS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Name:	malP EMBL ABO90339.1
Ordered Locus Names:	ASA_2289

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	825 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SN67 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 6E819A8D9C438C34	FASTA	825	93,476
	10 20 30 40 50 60 MATKKKTDQD LQLDKDQLKA SIVRHLRSTL GTSEQKASPE AWWKATAAAV NEQVYERLTR 70 80 90 100 110 120 TQQTHFKKDT RAIHYLSAEF LMGRLTSNNL HNLSLYKVCE EALGELGLEL TDLCEQEPDM 130 140 150 160 170 180 ALGNGGLGRL AACFIDSLAT LNYPAVGYGI HYEHGLFRQE IKDGRQIERP DSWREYGNPW 190 200 210 220 230 240 EICRPESVQE IPLYGYVETV FGDKGGLKKV WHAGRKIKGV PWDIPVVGFG GHTVNILRLW 250 260 270 280 290 300 ESRASEFFDW DVFNAGGYID SQAEKAQAET ISKVLYPNDE TDAGKELRLI QQYFFCACSI 310 320 330 340 350 360 KDIMRRYKRV HGSDFSNFAA QIAIQLNDTH PTVAIPELMR VLVDEEDLNW DAAWAICYRV 370 380 390 400 410 420 FSYTNHTLLP EALEKWSVSL FEKVLPRHLE VIYEINARFL SDLVEPKWPG NDAIKAKLSI 430 440 450 460 470 480 IEEGDVRKVR MGNLCVIGSS KVNGVAEIHS KLVKEDLFPE FAELWPEKMC NVTNGVTPRR 490 500 510 520 530 540 WLLACNPELA ELYNEVVGKE WPLQLDKLRA VTKFADDKAF QQQFMTIKRH NKEKLVKVIK 550 560 570 580 590 600 AETGIDVSAE AIFDVQIKRL HEYKRQQLNL IHIMALYRRL LANPDYDMHP RVFIFGSKAA 610 620 630 640 650 660 PGYKLAKDII YAINKLAERV NNDARIQGKL KVVFMPNYRV SLAEKLIPAA DVSEQISTAG 670 680 690 700 710 720 YEASGTGNMK MALNGAITIG TLDGANIEIA EEAGAENCAI FGLNVDEVKS LKARGYNPYD 730 740 750 760 770 780 FYYANSELKA VLDWFDTDYF TPGRPGELAS IKRSLLEGGD PYLTLADFAS YSDAHKLIDT 790 800 810 820 WYRDPALWAK KAIINSATMG KFNSDRSIQD YVDRIWNLTS CNVQG

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO90339.1.
RefSeq	YP_001142087.1. NC_009348.1.
3D structure databases
ProteinModelPortal	A4SN67.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SN67.
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4997809.
GenomeReviews	Gene locus ASA_2289 in contig CP000644_GR.
KEGG	asa:ASA_2289.
PATRIC	20790916. VBIAerSal2987_2243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0058.
HOGENOM	HBG444050.
OMA	NNDPRIG.
PhylomeDB	A4SN67.
ProtClustDB	CLSK2530410.
Family and domain databases
InterPro	IPR011833. Glycg_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
KO	K00688.
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02093. P_ylase. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4SN67_AERS4

Accession

Primary (citable) accession number: A4SN67

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)