Reviewed, UniProtKB/Swiss-Prot A4SML2 (DCD_AERS4)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	ASA_2067

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009674

Sequences

	Sequence		Length	Mass (Da)
	A4SML2-1 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: D736ABE711D6BAD3	FASTA	193	21,362
	10 20 30 40 50 60 MRLCDTDIER HLDEGKIVIE PRPGVERISG VSVDVLLGNE FRVFRDHTAP YIDLSGPNSE 70 80 90 100 110 120 MADAIDRVMS DEIHIPDGEA FYLHPGQLAL AVTYESVTLP ADIVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WSGRIVLEFY NGGKLPLALR PKMKIGALNF EMLSGPAARP YNKRENAKYK 190 SQQGAVASRI NQD

References

[1]

"The genome sequence of Aeromonas salmonicida subsp. salmonicida A449." Reith M.E., Singh R.K., Curtis B., Boyd J., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J., Johnson S., Brown L. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000644 Genomic DNA. Translation: ABO90134.1.
RefSeq	YP_001141882.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4SML2.
Genome annotation databases
GeneID	4996098.
GenomeReviews	Gene locus ASA_2067 in contig CP000644_GR.
KEGG	asa:ASA_2067.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GSRYQGQ.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_AERS4

Accession

Primary (citable) accession number: A4SML2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 15, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)