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Protein

Ribosomal RNA small subunit methyltransferase F

Gene

rsmF

Organism
Aeromonas salmonicida (strain A449)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(1407) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1407) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei149S-adenosyl-L-methionineUniRule annotation1
Binding sitei176S-adenosyl-L-methionineUniRule annotation1
Binding sitei194S-adenosyl-L-methionineUniRule annotation1
Active sitei247NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase FUniRule annotation (EC:2.1.1.178UniRule annotation)
Alternative name(s):
16S rRNA m5C1407 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmFUniRule annotation
Gene namesi
Name:rsmFUniRule annotation
Ordered Locus Names:ASA_2044
OrganismiAeromonas salmonicida (strain A449)
Taxonomic identifieri382245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000225 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000692701 – 476Ribosomal RNA small subunit methyltransferase FAdd BLAST476

Proteomic databases

PRIDEiA4SMI9.

Interactioni

Protein-protein interaction databases

STRINGi382245.ASA_2044.

Structurei

3D structure databases

ProteinModelPortaliA4SMI9.
SMRiA4SMI9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni125 – 131S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
COG3270. LUCA.
HOGENOMiHOG000218115.
KOiK11392.
OMAiDPLFHAG.

Family and domain databases

HAMAPiMF_01579. 16SrRNA_methyltr_F. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR031341. Methyltr_RsmF_N.
IPR001678. MeTrfase_RsmB/NOP2.
IPR027391. Nol1_Nop2_Fmu_2.
IPR011023. Nop2p.
IPR023267. RCMT.
IPR023545. rRNA_ssu_MeTfrase_F.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF17125. Methyltr_RsmF_N. 1 hit.
PF13636. Methyltranf_PUA. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00446. nop2p. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

A4SMI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHDNTYLPDH FLHHIAAIMP AHLSMDEFVA SCRRPLRRSI RVNTLKISVS
60 70 80 90 100
DFVMQMQPLG WQFDAVPWCE TGFWLTRADE SVPLGNTAEH LSGLFYIQEA
110 120 130 140 150
SSMLPVTALF ASDQVKRDGM LLDAAAAPGS KTTQIAALMN NQGMLVANEY
160 170 180 190 200
SSSRLKVLSA NIQRCGVTNV GMTHFDAKVF GQWLPETFDA ILLDAPCSGE
210 220 230 240 250
GTVRKDEDAL RNWSIESIDE IAAVQQGLLE SAFHALKPGG VLVYSTCTLS
260 270 280 290 300
QQENQAVCQS LLEKFGDALT LDSLADLFPN AEQACTPEGY LHVWPQIFDS
310 320 330 340 350
EGFFVARLRK HHSVPNTMFK PGKLGKFPFS PLPAKEAEPM LREIEANFGV
360 370 380 390 400
VPPGQLFGRN DEIWLFPHLF GQVQGKLRFD RIGIKLAETF KKGYRLTHEW
410 420 430 440 450
ALAYGDKATQ GVVELDSANA REFMMGRDVW PEQEAGTGEM IVRYQGHTLG
460 470
MGKWVGSRVK NALPRELVRD NNLFGA
Length:476
Mass (Da):52,947
Last modified:May 15, 2007 - v1
Checksum:iFA350993620439EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO90111.1.
RefSeqiWP_005311517.1. NC_009348.1.

Genome annotation databases

EnsemblBacteriaiABO90111; ABO90111; ASA_2044.
GeneIDi4997513.
KEGGiasa:ASA_2044.
PATRICifig|382245.13.peg.2009.

Similar proteinsi

Entry informationi

Entry nameiRSMF_AERS4
AccessioniPrimary (citable) accession number: A4SMI9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 15, 2007
Last modified: June 7, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome