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A4SM83 (AROC_AERS4) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:ASA_1932
OrganismAeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]
Taxonomic identifier382245 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Chorismate synthase HAMAP MF_00300
PRO_0000322382

Sequences

Sequence LengthMass (Da)Tools
A4SM83 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: C8D69D2876CAC985

FASTA36239,048
        10         20         30         40         50         60 
MAGNSFGQLF RVTTFGESHG LALGAVVDGC PPGLEISEAD LQIDLDRRKP GTSRYTTPRR 

        70         80         90        100        110        120 
EPDEVKILSG VFEGRTTGTS IGLLIENTDQ RSKDYSDIKD VFRPGHADYT YHQKYGQRDY 

       130        140        150        160        170        180 
RGGGRSSARE TAMRVAAGAI AKKYLKQMHG IEITGFLSQL GPIKAEGFDA AQIEQNPFFF 

       190        200        210        220        230        240 
PDAGKLEELD QYMRDLKKEG NSVGAKVQVI ATKVPVGLGE PVFDRLDADI AHAMMGINAV 

       250        260        270        280        290        300 
KGVEIGDGFA VVEQKGSEHR DEMTPAGFAS NHAGGILGGI SSGQDIVVSM ALKPTSSITV 

       310        320        330        340        350        360 
PGKTINTEGE AIEMITKGRH DPCVGIRAVP IAEAMLALVL MDHLLRHRAQ NQGVMTQTPQ 


LR

« Hide

References

[1]"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
BMC Genomics 9:427-427(2008) [PubMed: 18801193] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A449.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000644 Genomic DNA. Translation: ABO90005.1.
RefSeqYP_001141753.1. NC_009348.1.

3D structure databases

ProteinModelPortalA4SM83.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4SM83.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4996783.
GenomeReviewsGene locus ASA_1932 in contig CP000644_GR.
KEGGasa:ASA_1932.
PATRIC20790238. VBIAerSal2987_1915.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMASRFTTQR.
PhylomeDBA4SM83.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycASAL382245:ASA_1932-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_AERS4
AccessionPrimary (citable) accession number: A4SM83
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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