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A4SJB3 (GLSA_AERS4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:ASA_0837
OrganismAeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]
Taxonomic identifier382245 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Glutaminase HAMAP-Rule MF_00313
PRO_1000048320

Sites

Binding site641Substrate By similarity
Binding site1151Substrate By similarity
Binding site1591Substrate By similarity
Binding site1661Substrate By similarity
Binding site1901Substrate By similarity
Binding site2421Substrate By similarity
Binding site2601Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A4SJB3 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: D60AA488F2B5F7BB

FASTA30632,824
        10         20         30         40         50         60 
MVLSSELLAS ILAEVRPLLG QGKVADYIPA LAQVPADRLG MAVCTVEGEL FTAGDAFEPF 

        70         80         90        100        110        120 
SIQSISKALS LTLALTLYQE EEIWARVGKE PSGQPFNSLV QLEFEQGIPR NPFINAGALV 

       130        140        150        160        170        180 
VSDLLETRLT APRQRTLELV RRLSGNPAIM ADQVVARSEY QHSARNAAIA YLMKAYGNFE 

       190        200        210        220        230        240 
NEVDKVLQSY FNACAIRMSC VDLARAFIYL ANRGVPLGAG EPLLPARTTK QVNALLATCG 

       250        260        270        280        290        300 
LYDEAGDFAY RVGMPGKSGV GGGIMALIPG ELCVCVWSPE LNKAGNSLAG TAALELLAER 


LGRSIF 

« Hide

References

[1]"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A449.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000644 Genomic DNA. Translation: ABO88985.1.
RefSeqYP_001140733.1. NC_009348.1.

3D structure databases

ProteinModelPortalA4SJB3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING382245.ASA_0837.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO88985; ABO88985; ASA_0837.
GeneID4995587.
KEGGasa:ASA_0837.
PATRIC20788012. VBIAerSal2987_0836.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAMSIAVWS.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycASAL382245:GJJN-833-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_AERS4
AccessionPrimary (citable) accession number: A4SJB3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families