Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Aeromonas salmonicida (strain A449)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei543 – 5431UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciASAL382245:GJJN-572-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:ASA_0576
OrganismiAeromonas salmonicida (strain A449)
Taxonomic identifieri382245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
ProteomesiUP000000225: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 877877Phosphoenolpyruvate carboxylasePRO_1000025545Add
BLAST

Proteomic databases

PRIDEiA4SIM0.

Interactioni

Protein-protein interaction databases

STRINGi382245.ASA_0576.

Structurei

3D structure databases

ProteinModelPortaliA4SIM0.
SMRiA4SIM0. Positions 4-877.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4SIM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEKYAALRA NVGMLGQLLG KSIKDHQGQA FLDKIETIRQ LAKSSRKGNE
60 70 80 90 100
ADRERLLETL RTLSDDELLP VARAFSQFLN LANVAEQFHT ISRRCEEQVC
110 120 130 140 150
TPDPLEQMFA KLKASNLSQE AIIQAVRELD IDLVLTAHPT EVTRRTLIHK
160 170 180 190 200
HVQLNDCLEA LELSDLLPRE RDKILNRIEQ LVNQAWHTNE IREQRPTPVD
210 220 230 240 250
EAKWGFAVVE NSLWPAIPEF MRNLDERLQQ HLGVRLPLDA APVKFTSWMG
260 270 280 290 300
GDRDGNPFVT AKVTAEVLEL GRWMAVSLFY KDIKELTSEL SMSDCTDAVR
310 320 330 340 350
ERVGDHPEPY RALVRELREA LRETQEYLTA KVQGQVSESR DLITTTAQLR
360 370 380 390 400
EPLELCYHSM HACGMGNIAD GMLLDVLRKL ACFGIHLVKL DIRQDGERHG
410 420 430 440 450
QVFSELTRYL GMGDYAEWSE DDKQAFLLNE LNSRRPLIPT DWEPSDETRE
460 470 480 490 500
TIDTCRVIAQ HDPDAFGIYI ISMAGAPSDV LAVQLLLKEA GCKFRMPVAP
510 520 530 540 550
LFETQEDLMA GTAVMERLLS VDWYRGYIQG RQYVMIGYSD SAKDAGMMAA
560 570 580 590 600
GWAQYAAMES LVALAEASNL RLTLFHGRGG TVGRGGAPAH QAILSQPPGS
610 620 630 640 650
LRGGLRVTEQ GEMIRFKFGL PKVAIHSLNL YTSAVLEGNL LPPPKPKESW
660 670 680 690 700
RAVMEQLATV SCDHYRSIVR GHPDFVPYFR AATPEMELGK LPLGSRPAKR
710 720 730 740 750
KPNGGVESLR AIPWIFAWTQ NRLMLPAWLG AHKGLEHAIT DGQKSVLEEM
760 770 780 790 800
SRQWPFFRTR LEMLEMVFLK ADLWLAEYYD TRLVPQELWN LGKQLRQELA
810 820 830 840 850
DAIQIVLQLR PQGDLLDDQP WIKESINLRN PYTDPLNVLQ VELLGRSRSH
860 870
TETLHPELDQ ALMVTIAGIA AGMRNTG
Length:877
Mass (Da):99,049
Last modified:May 15, 2007 - v1
Checksum:iF02D83589517C14B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO88742.1.
RefSeqiYP_001140490.1. NC_009348.1.

Genome annotation databases

EnsemblBacteriaiABO88742; ABO88742; ASA_0576.
GeneIDi4995389.
KEGGiasa:ASA_0576.
PATRICi20787476. VBIAerSal2987_0581.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA. Translation: ABO88742.1.
RefSeqiYP_001140490.1. NC_009348.1.

3D structure databases

ProteinModelPortaliA4SIM0.
SMRiA4SIM0. Positions 4-877.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi382245.ASA_0576.

Proteomic databases

PRIDEiA4SIM0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO88742; ABO88742; ASA_0576.
GeneIDi4995389.
KEGGiasa:ASA_0576.
PATRICi20787476. VBIAerSal2987_0581.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciASAL382245:GJJN-572-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
    Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
    BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A449.

Entry informationi

Entry nameiCAPP_AERS4
AccessioniPrimary (citable) accession number: A4SIM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: January 7, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.