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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Aeromonas salmonicida (strain A449)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei543UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:ASA_0576
OrganismiAeromonas salmonicida (strain A449)
Taxonomic identifieri382245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000225 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000255451 – 877Phosphoenolpyruvate carboxylaseAdd BLAST877

Proteomic databases

PRIDEiA4SIM0

Interactioni

Protein-protein interaction databases

STRINGi382245.ASA_0576

Structurei

3D structure databases

ProteinModelPortaliA4SIM0
SMRiA4SIM0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238648
KOiK01595
OMAiPWVFGWT

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A4SIM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEKYAALRA NVGMLGQLLG KSIKDHQGQA FLDKIETIRQ LAKSSRKGNE
60 70 80 90 100
ADRERLLETL RTLSDDELLP VARAFSQFLN LANVAEQFHT ISRRCEEQVC
110 120 130 140 150
TPDPLEQMFA KLKASNLSQE AIIQAVRELD IDLVLTAHPT EVTRRTLIHK
160 170 180 190 200
HVQLNDCLEA LELSDLLPRE RDKILNRIEQ LVNQAWHTNE IREQRPTPVD
210 220 230 240 250
EAKWGFAVVE NSLWPAIPEF MRNLDERLQQ HLGVRLPLDA APVKFTSWMG
260 270 280 290 300
GDRDGNPFVT AKVTAEVLEL GRWMAVSLFY KDIKELTSEL SMSDCTDAVR
310 320 330 340 350
ERVGDHPEPY RALVRELREA LRETQEYLTA KVQGQVSESR DLITTTAQLR
360 370 380 390 400
EPLELCYHSM HACGMGNIAD GMLLDVLRKL ACFGIHLVKL DIRQDGERHG
410 420 430 440 450
QVFSELTRYL GMGDYAEWSE DDKQAFLLNE LNSRRPLIPT DWEPSDETRE
460 470 480 490 500
TIDTCRVIAQ HDPDAFGIYI ISMAGAPSDV LAVQLLLKEA GCKFRMPVAP
510 520 530 540 550
LFETQEDLMA GTAVMERLLS VDWYRGYIQG RQYVMIGYSD SAKDAGMMAA
560 570 580 590 600
GWAQYAAMES LVALAEASNL RLTLFHGRGG TVGRGGAPAH QAILSQPPGS
610 620 630 640 650
LRGGLRVTEQ GEMIRFKFGL PKVAIHSLNL YTSAVLEGNL LPPPKPKESW
660 670 680 690 700
RAVMEQLATV SCDHYRSIVR GHPDFVPYFR AATPEMELGK LPLGSRPAKR
710 720 730 740 750
KPNGGVESLR AIPWIFAWTQ NRLMLPAWLG AHKGLEHAIT DGQKSVLEEM
760 770 780 790 800
SRQWPFFRTR LEMLEMVFLK ADLWLAEYYD TRLVPQELWN LGKQLRQELA
810 820 830 840 850
DAIQIVLQLR PQGDLLDDQP WIKESINLRN PYTDPLNVLQ VELLGRSRSH
860 870
TETLHPELDQ ALMVTIAGIA AGMRNTG
Length:877
Mass (Da):99,049
Last modified:May 15, 2007 - v1
Checksum:iF02D83589517C14B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000644 Genomic DNA Translation: ABO88742.1
RefSeqiWP_005313775.1, NC_009348.1

Genome annotation databases

EnsemblBacteriaiABO88742; ABO88742; ASA_0576
GeneIDi4995389
KEGGiasa:ASA_0576

Similar proteinsi

Entry informationi

Entry nameiCAPP_AERS4
AccessioniPrimary (citable) accession number: A4SIM0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: May 23, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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