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A4SIM0 (CAPP_AERS4) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:ASA_0576
OrganismAeromonas salmonicida (strain A449) [Complete proteome] [HAMAP]
Taxonomic identifier382245 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas

Protein attributes

Sequence length877 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 877877Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025545

Sites

Active site1381 By similarity
Active site5431 By similarity

Sequences

Sequence LengthMass (Da)Tools
A4SIM0 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: F02D83589517C14B

FASTA87799,049
        10         20         30         40         50         60 
MNEKYAALRA NVGMLGQLLG KSIKDHQGQA FLDKIETIRQ LAKSSRKGNE ADRERLLETL 

        70         80         90        100        110        120 
RTLSDDELLP VARAFSQFLN LANVAEQFHT ISRRCEEQVC TPDPLEQMFA KLKASNLSQE 

       130        140        150        160        170        180 
AIIQAVRELD IDLVLTAHPT EVTRRTLIHK HVQLNDCLEA LELSDLLPRE RDKILNRIEQ 

       190        200        210        220        230        240 
LVNQAWHTNE IREQRPTPVD EAKWGFAVVE NSLWPAIPEF MRNLDERLQQ HLGVRLPLDA 

       250        260        270        280        290        300 
APVKFTSWMG GDRDGNPFVT AKVTAEVLEL GRWMAVSLFY KDIKELTSEL SMSDCTDAVR 

       310        320        330        340        350        360 
ERVGDHPEPY RALVRELREA LRETQEYLTA KVQGQVSESR DLITTTAQLR EPLELCYHSM 

       370        380        390        400        410        420 
HACGMGNIAD GMLLDVLRKL ACFGIHLVKL DIRQDGERHG QVFSELTRYL GMGDYAEWSE 

       430        440        450        460        470        480 
DDKQAFLLNE LNSRRPLIPT DWEPSDETRE TIDTCRVIAQ HDPDAFGIYI ISMAGAPSDV 

       490        500        510        520        530        540 
LAVQLLLKEA GCKFRMPVAP LFETQEDLMA GTAVMERLLS VDWYRGYIQG RQYVMIGYSD 

       550        560        570        580        590        600 
SAKDAGMMAA GWAQYAAMES LVALAEASNL RLTLFHGRGG TVGRGGAPAH QAILSQPPGS 

       610        620        630        640        650        660 
LRGGLRVTEQ GEMIRFKFGL PKVAIHSLNL YTSAVLEGNL LPPPKPKESW RAVMEQLATV 

       670        680        690        700        710        720 
SCDHYRSIVR GHPDFVPYFR AATPEMELGK LPLGSRPAKR KPNGGVESLR AIPWIFAWTQ 

       730        740        750        760        770        780 
NRLMLPAWLG AHKGLEHAIT DGQKSVLEEM SRQWPFFRTR LEMLEMVFLK ADLWLAEYYD 

       790        800        810        820        830        840 
TRLVPQELWN LGKQLRQELA DAIQIVLQLR PQGDLLDDQP WIKESINLRN PYTDPLNVLQ 

       850        860        870 
VELLGRSRSH TETLHPELDQ ALMVTIAGIA AGMRNTG 

« Hide

References

[1]"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen."
Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L.
BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A449.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000644 Genomic DNA. Translation: ABO88742.1.
RefSeqYP_001140490.1. NC_009348.1.

3D structure databases

ProteinModelPortalA4SIM0.
SMRA4SIM0. Positions 4-877.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING382245.ASA_0576.

Proteomic databases

PRIDEA4SIM0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO88742; ABO88742; ASA_0576.
GeneID4995389.
KEGGasa:ASA_0576.
PATRIC20787476. VBIAerSal2987_0581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycASAL382245:GJJN-572-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_AERS4
AccessionPrimary (citable) accession number: A4SIM0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families