A4SHM4 (A4SHM4_AERS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP-Rule MF_00123
EC=6.1.1.19 HAMAP-Rule MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP-Rule MF_00123

Gene names

Name:	argS HAMAP-Rule MF_00123 EMBL ABO88396.1
Ordered Locus Names:	ASA_0202 EMBL ABO88396.1

Organism

Aeromonas salmonicida (strain A449) [Complete proteome] [HAMAP] EMBL ABO88396.1

Taxonomic identifier

382245 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas › Aeromonas salmonicida › Aeromonas salmonicida subsp. salmonicida

Protein attributes

Sequence length	581 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00123
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00123

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP-Rule MF_00123
Cellular component	Cytoplasm HAMAP-Rule MF_00123
Ligand	ATP-binding HAMAP-Rule MF_00123 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP-Rule MF_00123 EMBL ABO88396.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SHM4 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 3CA9C6FC4C00C48D	FASTA	581	64,755
	10 20 30 40 50 60 MKEHIHHLLE QTVANLKSAG VLPADLEARV QVDRCKEKAH GDLATNLAML LAKPARKNPR 70 80 90 100 110 120 ELAAAIIENL PASDLIAKVE IAGPGFINFF FDQRWLAGQV ETMVTSANAN VKLPTPQTVV 130 140 150 160 170 180 VDYSAPNVAK EMAVHHIRST VLGDVAARAL EFLGHKVVRA NHIGDWGTQF GMLIAYLEKM 190 200 210 220 230 240 ANEHASDMAL KDLEAFYTQA KRCYDEDEAF AERARNYVVK LQGGDEYCRT MWKKLVDMTM 250 260 270 280 290 300 EQNQINYDRL NVSLTNKDIM GESMYNDMLP EIVADLKAKG LAVESEGATV VFLDEFKNKD 310 320 330 340 350 360 GEPMGVIIQK SDGGFLYTTT DIACAKYRYE TLGADRVMYF IDSRQHQHLM QAWTITRKAG 370 380 390 400 410 420 YVPESVPLEH HAFGMMLGKD GRPYKTRSGG TVKLVDLLNE AEERATALLE SRNSDLSAEE 430 440 450 460 470 480 KANVVNAIAM GAVKYADLSK NRTTDYIFDW DMMLSFEGNT APYLQYAYTR IQSIFRKANI 490 500 510 520 530 540 DASTLIGNVT LNEEAEEVLA QKLIQFSDAV NGVADKGMPH LLCTYLYELS GNFMTFYEAC 550 560 570 580 PINKDGVDEA TRQSRLLLCT ATAKVLKLGL GVLGIHTLER M

References

[1]

"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen." Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. BMC Genomics 9:427-427(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A449.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000644 Genomic DNA. Translation: ABO88396.1.
RefSeq	YP_001140144.1. NC_009348.1.
3D structure databases
ProteinModelPortal	A4SHM4.
ModBase	Search...
Protein-protein interaction databases
STRING	382245.ASA_0202.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABO88396; ABO88396; ASA_0202.
GeneID	4998021.
KEGG	asa:ASA_0202.
PATRIC	20786693. VBIAerSal2987_0210.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HOG000247212.
KO	K01887.
OMA	QGAKCVF.
ProtClustDB	PRK01611.
Enzyme and pathway databases
BioCyc	ASAL382245:GJJN-200-MONOMER.
Family and domain databases
Gene3D	3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001278. Arg-tRNA-ligase_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4SHM4_AERS4

Accession

Primary (citable) accession number: A4SHM4

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)