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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei37SubstrateUniRule annotation1
Binding sitei119SubstrateUniRule annotation1
Binding sitei152SubstrateUniRule annotation1
Binding sitei203ATPUniRule annotation1
Binding sitei294ATP; via carbonyl oxygenUniRule annotation1
Binding sitei325ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi354 – 357ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPHA290318:G1G8E-1852-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Cvib_1766
OrganismiChlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
Taxonomic identifieri290318 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000006700 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000765981 – 397Phosphoglycerate kinaseAdd BLAST397

Proteomic databases

PRIDEiA4SH15

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi290318.Cvib_1766

Structurei

3D structure databases

ProteinModelPortaliA4SH15
SMRiA4SH15
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni60 – 63Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

A4SH15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKKTLSDIT IQGKRILMRV DFNVPLNDER EITDDKRIVE ALPSIRKILD
60 70 80 90 100
NGGRLILMSH LGRPKGKVNP IFSLAPVAAK LSELIDTPVA MAEDCIGTEV
110 120 130 140 150
MQSALALQDG EVMLLENLRF HPEEEANDPE FAKELAALGE MYVNDAFGTA
160 170 180 190 200
HRAHASTEGI THFVPTAVAG YLIEKELMYL GKALEKPERP FVAILGGSKI
210 220 230 240 250
SGKIDVLENL FKKVDTVLIG GAMVFTFFKA MGLETGSSLV EDNKLELALS
260 270 280 290 300
LLEQAKNRNI KLLLPQDVIA APELSADAPF HAVSVKELEA GEMGLDIGPL
310 320 330 340 350
TIEAYRQEIL GARTILWNGP MGVFEIDSFA NGTFAVAEAM ALATAKGATT
360 370 380 390
IIGGGDSAAA VAKAGLASKM THISTGGGAS LEFLEGKELP GIAALND
Length:397
Mass (Da):42,406
Last modified:May 15, 2007 - v1
Checksum:iF3B5B684AD5A1F6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000607 Genomic DNA Translation: ABP37774.1
RefSeqiWP_011890996.1, NC_009337.1

Genome annotation databases

EnsemblBacteriaiABP37774; ABP37774; Cvib_1766
KEGGipvi:Cvib_1766

Similar proteinsi

Entry informationi

Entry nameiPGK_CHLPM
AccessioniPrimary (citable) accession number: A4SH15
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: April 25, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health