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Protein

Protoporphyrin ferrochelatase

Gene

Cvib_1664

Organism
Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Protoheme + 2 H+ = protoporphyrin + Fe2+.SAAS annotation

Pathwayi: protoheme biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes protoheme from protoporphyrin-IX.SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Protoporphyrin ferrochelatase (Cvib_1664), Protoporphyrin ferrochelatase (Cvib_1096)
This subpathway is part of the pathway protoheme biosynthesis, which is itself part of Porphyrin-containing compound metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes protoheme from protoporphyrin-IX, the pathway protoheme biosynthesis and in Porphyrin-containing compound metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseSAAS annotation
Biological processHeme biosynthesisSAAS annotation, Porphyrin biosynthesisSAAS annotation
LigandIronSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00252; UER00325.

Names & Taxonomyi

Protein namesi
Recommended name:
Protoporphyrin ferrochelataseSAAS annotation (EC:4.99.1.1SAAS annotation)
Gene namesi
Ordered Locus Names:Cvib_1664Imported
OrganismiChlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))Imported
Taxonomic identifieri290318 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000006700 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi290318.Cvib_1664.

Structurei

3D structure databases

ProteinModelPortaliA4SGR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ferrochelatase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000149048.
KOiK01772.
OMAiYLNHDVG.
OrthoDBiPOG091H041Q.

Family and domain databases

CDDicd00419. Ferrochelatase_C. 1 hit.
cd03411. Ferrochelatase_N. 1 hit.
InterProiView protein in InterPro
IPR001015. Ferrochelatase.
IPR033644. Ferrochelatase_C.
IPR033659. Ferrochelatase_N.
PANTHERiPTHR11108. PTHR11108. 1 hit.
PfamiView protein in Pfam
PF00762. Ferrochelatase. 1 hit.

Sequencei

Sequence statusi: Complete.

A4SGR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKKVAVILA AHGEAETDSF PENFSMIRHT FAHAGAVMNI PFPLQLAASV
60 70 80 90 100
FGGLKNLVEF RSSGYRSPQK HITRMQAERL GDELRRQSPG DDTLYEVSAA
110 120 130 140 150
YHAAPPFVED LLDETSGYDM QLLVTMSPVD SDLTAGRLQH LADRRSIAEN
160 170 180 190 200
NARPPVVISG FWDDPMLYRV YLNHLFSHAS GEEGPALLLT FHGTLVKDRK
210 220 230 240 250
GNEPGFRTGY PEILRMGSAL REAVRNDPRS PYQHVDIAYL NHQVGGTWTE
260 270 280 290 300
PSLLDSLREV AKSGITRADV FSVGYFSDGT EILRHAKEEA EASPVESVRL
310 320
IPCLNENEEF MKYLAGRVRE AVSNS
Length:325
Mass (Da):36,147
Last modified:May 15, 2007 - v1
Checksum:i3687A361FB087EBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000607 Genomic DNA. Translation: ABP37674.1.
RefSeqiWP_011890897.1. NC_009337.1.

Genome annotation databases

EnsemblBacteriaiABP37674; ABP37674; Cvib_1664.
KEGGipvi:Cvib_1664.
PATRICi21397864. VBIChlPha132153_1749.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000607 Genomic DNA. Translation: ABP37674.1.
RefSeqiWP_011890897.1. NC_009337.1.

3D structure databases

ProteinModelPortaliA4SGR5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290318.Cvib_1664.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP37674; ABP37674; Cvib_1664.
KEGGipvi:Cvib_1664.
PATRICi21397864. VBIChlPha132153_1749.

Phylogenomic databases

HOGENOMiHOG000149048.
KOiK01772.
OMAiYLNHDVG.
OrthoDBiPOG091H041Q.

Enzyme and pathway databases

UniPathwayiUPA00252; UER00325.

Family and domain databases

CDDicd00419. Ferrochelatase_C. 1 hit.
cd03411. Ferrochelatase_N. 1 hit.
InterProiView protein in InterPro
IPR001015. Ferrochelatase.
IPR033644. Ferrochelatase_C.
IPR033659. Ferrochelatase_N.
PANTHERiPTHR11108. PTHR11108. 1 hit.
PfamiView protein in Pfam
PF00762. Ferrochelatase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA4SGR5_CHLPM
AccessioniPrimary (citable) accession number: A4SGR5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: February 15, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.