A4SGC2 (A4SGC2_PROVI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABP37531.1
EC=2.4.1.182 EMBL ABP37531.1

Gene names

Ordered Locus Names:

Cvib_1520

Organism

Prosthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265)) [Complete proteome] [HAMAP]

Taxonomic identifier

290318 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	393 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABP37531.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SGC2 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 34483DA417C1DD59	FASTA	393	43,207
	10 20 30 40 50 60 MPKKLFVLAG EVSGDMHAAP AVARLVQEVP GLRVFGVGGE GLRRLGAELL YDTGQMSIMG 70 80 90 100 110 120 FFDVLKHAGF LRRVIRDLKA AVRREMPDAV LLVDYPGMNL IMAKFCRELG IPVIYYISPQ 130 140 150 160 170 180 VWAWKEGRVK AIGASIDRLL VIFRFEVDFF RKHGIDAEFV GHPVIEELSE VQLPPKEAFL 190 200 210 220 230 240 RAHGIGADAQ LVGLLPGSRK QEVSHIFPGM LKGARLLVGG RRVVFLMGRA PNLDGVVYRE 250 260 270 280 290 300 LEEYRDLRIV ECSAYEVMQY SDLGLVTSGT ATLEALCFGM PMVVLYRTGW LNYMIGRMVV 310 320 330 340 350 360 KLTSISLANI VAKGLGAKQQ AVPELIQDAA DGKGIFREAS RILDDPALAA AMRAELLEAR 370 380 390 AGLASESPSR RVAEVVEEYL VGTGRRGALK IKE

References

[1]

"Complete sequence of Prosthecochloris vibrioformis DSM 265." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 265.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000607 Genomic DNA. Translation: ABP37531.1.
RefSeq	YP_001131033.1. NC_009337.1.
3D structure databases
ProteinModelPortal	A4SGC2.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SGC2.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4971059.
GenomeReviews	Gene locus Cvib_1520 in contig CP000607_GR.
KEGG	pvi:Cvib_1520.
PATRIC	21397548. VBIChlPha132153_1599.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	PDFNLGL.
PhylomeDB	A4SGC2.
ProtClustDB	CLSK637261.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4SGC2_PROVI

Accession

Primary (citable) accession number: A4SGC2

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)