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A4SG83 (HIS3_PROVI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length137 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(5-phospho-beta-D-ribosyl)-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D-ribosylamino)methylideneamino)imidazole-4-carboxamide. HAMAP-Rule MF_01021

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9. HAMAP-Rule MF_01021

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01021.

Sequence similarities

Belongs to the PRA-CH family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Histidine biosynthesis
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processhistidine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphoribosyl-AMP cyclohydrolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 137137Phosphoribosyl-AMP cyclohydrolase HAMAP-Rule MF_01021
PRO_1000084183

Sequences

Sequence LengthMass (Da)Tools
A4SG83 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: F7D5117C53C40A32

FASTA13715,705
        10         20         30         40         50         60 
MGENEGIDKS FLDTVKFDDR GLIPAIVQDH ETGKVLMMAW MNRESLEMTL ERKKACYWSR 

        70         80         90        100        110        120 
SRNKLWLKGE SSGNMQEVFD ILIDCDGDTL ILKVSQIGGA CHVGYHSCFY RKVNEDGSMQ 

       130 
ICDTLMFNPE EVYGKKH 

« Hide

References

[1]"Complete sequence of Prosthecochloris vibrioformis DSM 265."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 265.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000607 Genomic DNA. Translation: ABP37492.1.
RefSeqYP_001130994.1. NC_009337.1.

3D structure databases

ProteinModelPortalA4SG83.
SMRA4SG83. Positions 22-116.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290318.Cvib_1481.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP37492; ABP37492; Cvib_1481.
GeneID4970236.
KEGGpvi:Cvib_1481.
PATRIC21397466. VBIChlPha132153_1559.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0139.
HOGENOMHOG000277504.
KOK01496.
OMAHEPGIAC.
OrthoDBEOG6PGKB6.

Enzyme and pathway databases

BioCycCPHA290318:GHNQ-1519-MONOMER.
UniPathwayUPA00031; UER00008.

Family and domain databases

HAMAPMF_01021. HisI.
InterProIPR026660. PRA-CH.
IPR002496. PRib_AMP_CycHydrolase_dom.
[Graphical view]
PfamPF01502. PRA-CH. 1 hit.
[Graphical view]
ProDomPD002610. PRA_CycHdrlase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameHIS3_PROVI
AccessionPrimary (citable) accession number: A4SG83
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways