Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:Cvib_1288
OrganismiChlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
Taxonomic identifieri290318 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000006700 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000773111 – 319Methionyl-tRNA formyltransferaseAdd BLAST319

Interactioni

Protein-protein interaction databases

STRINGi290318.Cvib_1288

Structurei

3D structure databases

ProteinModelPortaliA4SFP1
SMRiA4SFP1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni116 – 119Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

A4SFP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVTPLRLIF MGTPDFAVPS LQAIVDASLP VEVVQVVTAP DRPRRKKNAE
60 70 80 90 100
AEPTPVKSLA LQLGLPVLEV EDVKDPGFAE AVRRLQPDVI VVAAFRILPP
110 120 130 140 150
AVYGAARLGA FNLHASLLPA YRGAAPINHA LIEGERESGV TTFFLQRQVD
160 170 180 190 200
TGNIILKKST PINSMENATQ LAERLSQIGA EAVVETLRLI AEGTVEVSAQ
210 220 230 240 250
DESLVSKAPK LTRENTRIDW NQSAEDLHNF IRGLAMRPTA WTTLGGKNFK
260 270 280 290 300
IFQSAPAPAV PATSCGKPGT MLIEGGCLYA SGTDGWIEIL SLQLEGKRPM
310
DAGEFLRGFR AESGVLFGS
Length:319
Mass (Da):34,340
Last modified:May 15, 2007 - v1
Checksum:i9EC9B74EC43556E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000607 Genomic DNA Translation: ABP37300.1

Genome annotation databases

EnsemblBacteriaiABP37300; ABP37300; Cvib_1288
KEGGipvi:Cvib_1288

Similar proteinsi

Entry informationi

Entry nameiFMT_CHLPM
AccessioniPrimary (citable) accession number: A4SFP1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: April 25, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health